Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 127 for “"deformability"”.
-
Erythrocyte deformability as assessed by nuclepore filters
Erythrocyte deformability characteristics were assessed by passing red cell suspensions through Nuclepore polycarbonate filters having pore diameters of 3 ym. with pore lengths of 12 ym. During flow through these filters, at a constant flow rate of 2.17 cc/min., the pressure drop across the filter …
-
Jointed rock mass deformability : a probabilistic approach
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1979.
-
Tumor cell deformability in the metastatic cascade
… Here, we measure the physical changes in the deformability of tumor cells, indicated by the length of time required to pass through a microfluidic constriction in a suspended microchannel resonator (SMR), as related to different stages of the metastatic process-particularly, in an …
-
Shear strength and deformability of rock joints
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1979.
-
Optical deformability : micromechanics from cell research to biomedicine
… properties of dielectric materials. This optical deformability was exploited for the measurement of cellular elasticities with a novel micromanipulation device based on a two-beam fiber-based laser trap, the optical stretcher, which can generate surface forces from 1 pN–1 nN at frequencies ranging …
-
Deformability of Plasmodium falciparum parasitized red blood cells
… Several pathologic conditions alter RBC deformability that can result in abnormal circulation behavior. In the present work, altered RBC deformability caused by invading Plasmodium falciparum parasites, which are responsible for the disease malaria, is evaluated. P. falciparum parasitized …
-
Ductility and deformability of FRP strengthened reinforced concrete structures
There are many structures in need of strengthening and upgrading and the need for this is due to a number of factors:<br/><br/>• Structural deterioration over time<br/>• Traffic volume increases<br/>• Increases in allowable maximum vehicle weights<br/>• Poor maintenance<br/>• Poor construction …
-
The relevance of red blood cell deformability in the pathophysiology of blood disorders
… as one of the direct consequences of reduced RBC deformability. On the other hand, deformability is also indirectly impacting on RBC functionality through its complex connections with underlying molecular mechanisms. With the aid of microfabrication and microfluidic, we are able to perform …
-
Effects of drugs which alter blood cell deformability in circulatory shock produced by endotoxin
… vascular occlusive disease by increasing RBC deformability and has been reported to improve survival in experimental hemorrhagic, septic and endotoxic shock. In the present investigation, the effects of pentoxifylline on endotoxin-induced mortality, disseminated intravascular coagulation …
-
Deformability and Dynamics in Linear and Looped/Supercoiled DNA with Implications for Damage Sensing
… topological changes are expected to impact DNA deformability and damage recognition. We employed advanced fluorescence approaches to study protein-DNA dynamics on biologically relevant timescales, identified DNA features enabling damage recognition, and unveiled how looping/supercoiling alters …
-
Applying a microfluidic 'deformability cytometry' to measure stiffness of malaria-infected red blood cells at body and febrile temperatures
… blood vessel, capillaries and splenic cords; RBC deformability is therefore crucial in maintaining normal blood circulation. During falciparum malaria, parasite proteins interact with the spectrin network of host RBCs, moderately stiffening the ring stage infected cells (rings). The subtle …
-
Microfluidic devices for analysis of red blood cell mechanical properties
Decreased deformability of human red blood cells (RBCs) is both a cause of disease and biomarker for disease (1). To traverse blood capillaries, the biconcave disk-shaped RBC must deform dramatically, since the diameter of the unconstrained RBC is larger than that of the capillaries. If the RBC …
-
Aktivität und Bedeutung der erythrozytären NOS bei kardiovaskulären Risikofaktoren
… regulated by similar mechanism and modulates RBC deformability. It was unknown wether RBC-NOS activity is changed in cardiovascular diseases and wether these changes are involved in reduced RBC deformability. Until now, the influence of NO on microcirculation has been proved in vitro only. In this …
-
Bestimmung des Formänderungsvermögens bei der Kaltmassivumformung
… prediction of the workpiece material deformability in cold forming processes possible. Using the current fracture criteria the moment of a crack initiation is not predictable. Such a numeric determination of the deformability would afford an improved economic interpretation of cold …
-
Biophysical Studies Aimed at Potential Therapies of Hemoglobin Associated Diseases
… cell disease (SCD): oxygen affinity and RBC deformability. A Hemox Analyzer, a dual-wavelength spectrophotometer, was used to measure oxygen affinity in sRBC treated with a potential drug intended to improve oxygen affinity. Deformability, the ability of the cells to elongate when exposed to …
-
Effect of Storage on the Elastic Properties of the Red Cell Membrane
… tests for predicting red blood cell survival is deformability.</p> <p>This study applies a recently developed method of measuring deformability to assess changes in stored blood. In brief, the method involves drawing a "mini" unit of blood from each of three normal healthy individuals. …
-
Fließverhalten des Blutes bei geriatrischen Patienten : eine Beurteilung anhand des Aachener Risikoprofils und der Vollblutdichte
… aggregation, plasma viscosity and erythrocyte deformability ) and the whole blood viscosity. In addition we wanted to know if it is possible to identify those patients who need a hemorheological therapy. Furthermore it was tested if variations of the Aachen rheology profile can be recognized by …
-
The effects of membrane and cytoskeletal mechanics on cell adhesiveness
… Specifically, we addressed how membrane deformability, which we demonstrate is critically dependent upon tethering to the cytoskeleton, could impact a whole cell adhesion assay. To modify membrane deformability, we treated cells with the pharmacological agents phalloidin, Latrinculin B, …
-
Biophysical responses of lymphocytes to environmental stress
… properties, such as mass, volume, density and deformability using a suspended microchannel resonator (SMR) can help characterize cellular behavior and physiological role. Here, we expand upon this previous work to demonstrate the necessity of measuring multiple parameters simultaneously to …
Page 1 of 7