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Showing 1 to 3 of 3 for “"defasciculation"”.

  1. Inhibition of Retinoic Acid Receptors Results in Defasciculation of the Trigeminal Nerve in Xenopus laevis

    … is downregulated just prior to the observed defasciculation phenotype. The pattern of expression of these genes combined with known expression of NT-3 receptors allows us to suggest a model whereby RA signaling regulates Sema4B, ALCAM and NT-3, which support the survival, guidance and …

    vcu Repository record for Inhibition of Retinoic Acid Receptors Results in Defasciculation of the Trigeminal Nerve in Xenopus laevis (opens in a new tab)

  2. Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain

    … melanogaster Atg1 also promote axonal growth and defasciculation, and disruption of these genes results in defects in axon guidance in invertebrates. Germline Ulk1/2-deficient mice die perinatally. Therefore, we used a conditional-knockout approach to investigate the roles of ULK1/2 in the brain. …

    tenn-hsc Repository record for Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain (opens in a new tab)

  3. Balancing growth and repulsion: Slit proteolysis generates diverse signals in axon guidance

    … is required for longitudinal axon fasciculation. Defasciculation and guidance errors in tok mutants are fully rescued by expression of Slit-N, but not Slit-C, suggesting that Slit is the primary substrate for Tok at the CNS midline. We determine that neither Slit-N nor Slit-C are capable of …

    unr Repository record for Balancing growth and repulsion: Slit proteolysis generates diverse signals in axon guidance (opens in a new tab)