Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"decidual"”.
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Hormonal control of decidual cell response in the rat
Digitized by Kansas State University Libraries
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Receptor-dependent phagocytosis of <i>Clostridium sordellii</i> by human decidual macrophages
<p><em>Clostridium sordellii</em> is an emerging pathogen associated with highly-lethal female reproductive tract (FRT) infections following childbirth, abortion, or cervical instrumentation. Gaps in our understanding of the pathogenesis of <em>C. sordelli</em>i infections present major challenges …
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Characteristics of decidual macrophages and Hofbauer cells in placentas of HIV positive women on antiretroviral therapy
… of maternal uterine-derived macrophages, the decidual macrophages and the foetal placental-derived macrophages, the Hofbauer Cells (HCs) in pregnancies complicated by maternal viral infections. The immune mechanisms associated with the high prevalence of adverse birth outcomes amongst HIV-1 …
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Role of transcription factor Runx1 in uterine stromal cell differentiation and maternal-fetal interaction during mouse pregnancy
… differentiation of endometrial stromal cells to decidual cells, a process known as decidualization, is essential for the establishment of pregnancy. The decidual tissue produces multitude of factors that control a variety of physiological processes at the fetal-maternal interface, such as …
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Estrogen signaling during decidualization
… blastocyst in the differentiated endometrium. Decidualization, a signatory event during this process is characterized by the deciduous transformation of fibroblast endometrial stromal cells to morphologically and functionally unique decidual cells along with the formation of extensive …
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The Role of the PD-1 Immunoreceptor in Pregnancy
… PD-1 is preferentially expressed on human decidual T cells and B7-H1 inhibits the inflammatory cytokine production of activated decidual T lymphocytes. In addition, possibly through B7-H1:PD-1 interactions, trophoblasts induce regulatory T cell expansion in vitro. Finally, in murine …
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The role of Ras-related C3 botulinum toxin substrate 1 (RAC1)-dependent pathway in the regulation of uterine function during early pregnancy
… stromal cells differentiate into specialized decidual cells, which become secretory and support the growth of the embryo before placentation. At the same time, new blood vessels begin to form in the maternal decidua from pre-existing vasculature. This process termed angiogenesis is critical …
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Physical Factors Regulating Human Trophoblast Invasion
… of cells. Despite invasion of EVT cells through decidual tissue rich in extracellular matrix (ECM) proteins, there has been no study investigating how tissue stiffness might regulate EVT invasion. Oxygen has also long been investigated as a regulator for trophoblast invasion, but evidence is …
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Revisão taxonômica de Dipsas Laurentis, 1768 (Serpentes, Colubridae) de ocorrência na Mata Atlântica
… in the southeast Brazil associated to semidecidual and decidual forests; 2) the realocation of D. indica bucephala (Shaw, 1802) in the sinonimy of D. indica indica Laurenti, 1768; 3) the elevation of D. indica petersi Hoge & Romano, 1975 to the species levei; 4) the redescription of Dipsas …
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The role of ERα in the uterus during embryo implantation and in the ovary during ovarian tumorigenesis
… receptor (PR). By employing artificially induced decidualization we know that ERalpha in the uterine stromal cells is essential for proliferation and decidualization. To date very few molecules have been shown to be regulated by estrogen in the uterine stromal cells that are essential for …
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Role of Msx homeobox genes in uterus during embryo implantation
… Msx homeobox genes during uterine stromal cell decidualization. As the embryo attaches to the uterine wall and invades into the stromal bed, the stromal cells surrounding the implanting blastocyst differentiate into decidual cells in a process known as decidualization. This process is critical …
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Innate Lymphoid Cell Diversity in Pregnancy and Ovarian Cancer
… are identifiable including three main subsets of decidual NK cells (dNK), dNK1-3. The most abundant subset, dNK1, express receptors for HLA class I found on invading extravillous trophoblast (EVT) including Killer-cell Ig-like receptors (KIR), LILRB1 and NKG2A. In contrast to dNK2 and dNK3, dNK1 …
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Molecular mechanisms regulating implantation
… followed by invasion of the blastocyst into a decidualizing stroma. These stages are tightly regulated by steroid hormones Estrogen (E) and Progesterone (P). Genomic profiling in mice has uncovered novel steroid regulated genes in the uterine luminal epithelium and also in the stroma which …
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ROLES OF HAND2 TRANSCRIPTION FACTOR IN UTERINE RECEPTIVITY AND DECIDUALIZATION
… the endometrial tissue undergoes the process of decidualization to support the anchoring of the blastocyst and provides the blastocyst with nutrition until the fully functional placenta is formed. Although the process of implantation and decidualization are under control of progesterone and …
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The expression of Heat Shock Protein 70 in the placental tissue with preeclampsia
… extravillous trophoblast in basal layer and decidual cell. And according to the intensity of immunostaining, we compared these three groups. Western blot analysis was performed and the quantification and comparison of Hsp70 were done in placental tissue among the three group of patients. …
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Inflammatory Mediators Associated with Pre-eclampsia
… levels of NF-kB, p-JNK and iNOS in the placental decidual tissue of both groups. Samples from preeclampsia patients had higher levels of NF-kB, p-JNK and iNOS than normal group. In addition, analysis of mRNA levels showed that although Patient group had higher NF-kB, iNOS, COX-2 mRNA levels than …
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Progesterone receptor targets play critical roles in maintaining pregnancy and disease prevention
… IR, is critical for inducing the expression of decidual markers and the changes in cell morphology characteristic of stromal differentiation. We also show that IRS2 promotes expression and membrane localization of glucose transporters (GLUT), allowing for increased glucose movement into the cell …
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A prospective study of implantation, maternal cardiovascular function and pregnancy outcome
… an inability to study events at the trophoblast-decidual interface in vivo. The primary objective of this study was to test the feasibility of being able to conduct and complete a prospective study from prior to pregnancy to the postpartum period combining measures of ovulation, implantation, …
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Steroid Hormone Regulation of Implantation
… is that E plays minimal role in the process of decidualization. Our studies show prominent expression of aromatase, the key enzyme involved in E synthesis, in the pregnant uterus during decidual phase of gestation. Studies in chapter II of the thesis describe the spatiotemporal expression …
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Mechanisms underlying establishment and maintenance of pregnancy
… and DiNP affect stromal cell differentiation and decidual angiogenesis, significant disorganization of the placental layers was only observed in the DiNP-treated mice. Interestingly, the fetuses from the DiNP group that do manage to survive in the sub-optimum uterine environment, though weigh less …
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