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Showing 1 to 4 of 4 for “"decellularized liver"”.
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A Nanoindentation Device and the Scale-Dependent Mechanical Properties of Native and Decellularized Liver Tissue
… the biomechanical properties of perfused decellularized liver scaffolds and compare them to perfused native tissue properties on both a macro and nano-scale. To accomplish this goal, a novel Nano-Tissue Indenter (NTI) was constructed that can be used to perform nanoindentation on virtually …
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Effects of Liver Extracellular Matrix Gel Stiffness on Primary Hepatocyte Function
… term function and viability of cells. Primary liver epithelial cells, or hepatocytes, are easily isolated in large quantities. However, these cells quickly lose viability and function once removed from the native organ. In order to support hepatocyte phenotype in culture, decellularized liver …
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A THREE DIMENSIONAL MODEL OF HUMAN HEPATO-BILIARY ORGANOGENESIS
… have emerged aimed at generating functional liver tissue by using decellularized liver scaffolds repopulated with liver cells. The quest continues for identifying the best cell source for liver tissue engineering, but one cell source in particular, human fetal liver progenitor cells (hFLPCs), …
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From iPSCs to Engineered Heart and Liver Models: Modulating Genetic and Extracellular State for Maturity
The heart and liver are central to human physiology yet remain major sites of drug-induced toxicity, driving the need for robust, scalable, and physiologically relevant in vitro models. Induced pluripotent stem cell (iPSC)–derived hepatocyte-like cells (HLCs) and cardiomyocytes (iPSC-CMs) offer …