Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"deAMPylation"”.
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Post-translational regulation of BiP by FICD-mediated AMPylation and deAMPylation
… adjust BiP’s activity through AMPylation and deAMPylation. These two mutually antagonistic reactions, catalysed by the single active site of FICD, are reciprocally regulated by an oligomeric state-dependent switch. Under conditions of low unfolded protein load this bifunctional (monomeric) Fic …
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Genetic Analysis of Fic-Mediated BiP AMPylation in Photoreceptors
… ER-resident Fic protein catalyzes AMPylation or deAMPylation of BiP, the major ER chaperone. This work elucidates a critical role of the reversible AMPylation of BiP in maintaining the Drosophila visual system in response to constant light-induced stress. In response to extended light exposure, …