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Showing 1 to 3 of 3 for “"de novo assembler"”.
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Efficient Synergistic De Novo Co-Assembly Of Bacterial Genomes From Single Cells Using Colored De Bruijn Graph
… displacement</p> <p>amplification (MDA), has made it possible to sequence and assemble bacterial</p> <p>genomes from a single cell. However, the quality of single cell genome assembly has</p> <p>not yet reached the quality of normal multi-cell genome assembly due to the coverage</p> <p>bias …
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De Novo Assembly of Genomes in Microbiomes: From Amplicons to Whole-Genome Shotgun Sequencing
In recent decades, the rapid progress of DNA sequencing technologies has greatly propelled metagenomics research. However, a critical bottleneck in current bioinformatics investigations is the assembly of metagenome at the strain-level resolution. This is indispensable for gaining profound insights …
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Rekonstrukce repetitivních elementů DNA
… velké množství repetitivních struktur. Jejich detekce a sestavení patří dnes k hlavním výzvám bioinformatiky. Tato práce obsahuje hlavní klasifikaci repetitivní DNA a představuje implementaci nového de novo assembleru, zaměřeného na hledání a sestavení LTR retrotranspozonů a satelitní DNA. …