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Showing 1 to 2 of 2 for “"database search program"”.
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Reverse engineering and optimisation of the BLASTP program
The BLASTP (Basic Local Alignment Search Tool for Proteins) is a popular protein database search program. The BLASTP algorithm consists of three steps: (1) Constructing the set of neighbourhood words, (2) Scanning a database sequence for word hits, and (3) Extending a word hit. By using a reverse …
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Evaluation of database search programs for accurate detection of neuropeptides in tandem mass spectrometry experiments
Programs to identify proteins in tandem mass spectrometry experiments are not optimized to identify neuropeptides and other peptides resulting from the processing of prohormones. This is due to the unique characteristics of neuropeptides including release after complex processing of prohormones, …