Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"daidzein"”.
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The symbiotic interaction of Bradyrhizobium japonicum with bambara groundnut and cowpea and the effects of NOD gene-inducers, daidzein and genistein
… additional nod geneinducer compounds. Both daidzein and genistein are nod gene-inducers for rhizobia nodulating cowpea, bambara groundnut, soybean and the common bean.
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Identifizierung und Charakterisierung der Isoflavon-umsetzenden Enzyme aus dem humanen Darmbakterium Slackia isoflavoniconvertens
… zeigen für die in Soja enthaltenen Isoflavone Daidzein und Genistein eine präventive Wirkung bezüglich hormon-abhängiger und altersbedingter Erkrankungen, wie Brust- und Prostatakrebs, Osteoporose, Herz-Kreislauf-Erkrankungen sowie des menopausalen Syndroms. Die Metabolisierung und …
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Beurteilung von Phyto- und Xenoöstrogenen am Beispiel ausgewählter Substanzen
Bei Daidzein und Bisphenol A handelt es sich um zwei Vertreter einer Klasse von Stoffen, die als „Umwelthormone“ (engl. endocrine disrupter) bezeichnet werden. Aus der Gruppe der Phytoöstrogene wurde Daidzein als wichtiger Vertreter, der in hohen Konzentrationen in vielen Nutzpflanzen und …
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Factors Influencing Early Embryonic Development in the Pig
… study indicate that the phytoestrogens, daidzein and genistein at concentrations (0, 10 nM, 30 nM, 100 nM, 300 nM, 1 muM and 3 muM) had no developmental effect on pig embryos, however pig embryos cultured with 3 muM daidzein may improve blastocyst formation over control embryos. Further …
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THE EFFECTS OF ESTROGENIC COMPOUNDS ON ADIPOGENESIS VIA PPARγ AND CANONICAL WNT SIGNALING
… acid, BDDA) and natural (i.e., genistein and daidzein) xenoestrogens in the protection against obesity-related pathologies. Bisdehydrodoisynolic acid (BDDA) reduced weight gain and adiposity, as well as improved lipid homeostasis in obese rodents. Alternatively, phytoestrogens, such as …
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Effect of phytoestrogens on breast and prostate cancer cell lines – potential implications for bone metastasis
… Results showed that phytoestrogens genistein and daidzein significantly reduced prostate cancer cell viability (PC3 cells) with concentration 10-7 M (15 %, P = 0.01) and 10-6 M (11%, P = 0.04) for genistein and for daidzein the decrease in cell number was (18%, P value = 0.04) for 10-8 M and (22 …
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Estrogenic and androgenic endocrine disrupting activity and risk assessment of phytoestrogens in Kenyan soya-based weaning flours
… the transcription activity of ten PEs (apigenin, daidzein, daidzin, genistein, genistin, enterodiol, equol, formononetin, glycitein and matairesinol) and in the Kenyan based gruel/flour extracts. A modified Hygiene Based Margin of Safety (HBMOS) method was used to estimate the estrogenicity due to …
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Genotoxic effects of oestrogens and nano-NSAIDs: Genotoxic effects of oestrogens in vivo and nano- and bulk forms of NSAIDs on blood samples from prostate cancer patients
… administered oestrogens (17β- oestradiol, daidzein, diethylstilboestrol, genistein, and equol), were examined. Male hooded- Lister rats were used to examine to what extent DNA damage occurred. The alkaline Comet assay was the chosen method used to assess double-strand DNA breakage by …
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The effect of isoflavone supplementation on cardiovascular disease parameters in men undergoing 80% VO₂pk exercise
… Isoflavones found in soy, such as genistein and daidzein are reported to have potent antioxidant properties and have been shown to inhibit LDL oxidation in vitro. Although there is a strong base of data that supports the correlation between soy consumption, cholesterol reduction and …
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Soybean (Glycine max (L.) Merr.); nodulation mutant characterization: Role of isoflavonoid, nitrate, and abscisic acid in nodulation control
Isoflavonoids (daidzein, genistein, and coumestrol) are known to be inducers of nod genes in Bradyrhizobium japonicum. This study evaluated the effect of inoculation and nitrogen on isoflavonoid concentration in soybean (Glycine max (L.) Merr.) root extracts from selected hypernodulating mutants …
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EVALUATION OF YAK-KONG SOYBEAN (GLYCINE MAX) FOR ITS PHENOLICS AND METABOLITES WITH A FOCUS ON ATHEROSCLEROSIS PREVENTION
… (7,8,4’-THI), a hydroxylated daidzein metabolite, was exclusively detected with the highest amount (average 5.1 μM) and average 574.3 ± 112.8 area under the curve within 240 min. In contrast to daidzein and daidzin, 7,8,4’-THI significantly prevented adhesion of THP-1 monocytes …
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Reducing the risk of prostate cancer with tomato and soy bioactives
… of the microbial-metabolite, equol, from daidzein. A TRAMP study from our lab suggested that a 2% soy germ diet reduced PCa incidence by 34%. The same study observed that prostatic equol concentrations were 39 times greater than prostatic genistein and 3 times higher than prostatic …
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Isoflavonoid induction and nitrogen assimilation in AM colonized red clover
… (3) contents of isoflavonoids (e.g. genistein, daidzein, biochanin A, and formononetin); and (4) contents of these four isoflavonoids over time and with a hormonal factor, jasmonic acid (JA). To accomplish these objectives, four greenhouse experiments were performed. The overall results indicate …
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Characterization of antioxidant activities of soybeans and assessment of their bioaccessibility after in vitro digestion
… % recovery, respectively. Aglycones, including daidzein and genistein, were recovered at 37 % and 73.7 %, respectively, after in vitro digestion. In this study, daidzin was the most stable and bioaccessible isoflavone determined using the in vitro digestive system. Among the aglycones, genistein …
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Stability of bioactive isoflavones and glycolytic enzymes produced by probiotic bacteria in soy based food during processing and storage
… at all the storage temperatures. Genistein and daidzein were much more stable than glycitein and had almost similar degradation pattern, despite differences in their concentrations in the fermented soymilk. It was, however, observed that 4°C was the most suitable storage temperature for the …
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Quantitative analysis and metabonomic study of phytoestrogens in Africans
… four isoflavones (formoinonetin, biochanin A, daidzein, genistein), one coumestan (coumestrol), and two lignans (secoisolariciresinol and matairesinol). The methods were applied to quantitate the phytoestrogen content in six African staple foods: beans, cassava, plantain, pumpkin leaves 'ugu', …
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Isotopic labeling of isoflavones from plant cell and organ culture for metabolic tracking in animal models
… by HPLC-ESI-MS and found to contain puerarin, daidzein, and puerarin glucuronide, which suggests that kudzu isoflavones may be able to have a role in promoting bone health. To improve kudzu isoflavone yields in vitro for further studies, kudzu hairy root cultures were elicited with acetate and …
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Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles
… metabolite produced by microbial conversion of daidzein, a major isoflavone phytoestrogen in soybean, in the gut of some humans and many animal species. Previous studies indicate that isoflavones and their metabolites can affect endogenous estradiol production, action, and metabolism via several …
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Soy Isoflavone Supplementation Does Not Alter Lymphocyte Proliferation and Cytokine Production In Postmenopausal Women
… addition, plasma concentrations of genistein and daidzein were quantified at baseline and at the end of the intervention period. Despite high individual variability among subjects, there was a significant increase (p<0.005) in plasma isoflavone concentration in the supplemented group. However, all …
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The Phytoestrogen Genistein Induces Thymic and Immune Changes: A Human Health Concern
… effects of the soy isoflavones genistein and daidzein. Here we show that subcutaneous genistein injections in ovariectomized adult mice produced dose-responsive decreases in thymic weight of up to 80%. Genistein's thymic effects occurred through both estrogen receptor (ER) and non-ER mediated …
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