Global ETD Search
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Showing 1 to 4 of 4 for “"daf-6"”.
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The Roles of daf-6 and Cell-Cell Interactions in Sensory Organ Morphogenesis
… in the amphid sensory organ. First, the gene daf-6 is required cell autonomously during amphid lumen formation. daf-6 encodes a Patched-related protein that is a member of a previously uncharacterized sub-family of sterolsensing domain containing proteins. Interestingly, daf-6 is expressed and …
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IGDB-2, an IG/FNIII Protein, Binds the ION Channel LGC-34 and Controls Sensory Compartment Morphogenesis in C. Elegans
… into some of these developmental processes. DAF-6, a Patched-related protein, was previously shown to be required in amphid glia to restrict sensory compartment size. LIT-1, a Nemo-like kinase, and SNX-1, a retromer component, antagonize DAF-6 and promote compartment expansion. My work here …
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Sensory Organ Morphogenesis in Caenorhabditis Elegans
… amphid, I was able to uncover a role for daf-6/Patched, an established regulator of amphid morphogenesis, in restricting the size of the sensory compartment. Second, I sought to identify genes acting in the opposite direction, in expanding the sensory compartment, by cloning and …
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IR Laser-Induced Gene Expression for Tracking Development of Single Embryonic Neurons and Glia in C. Elegans
… by performing cell-specific rescues, determining DAF-6/Patched-related site of action during sensory-organ development. Finally, I demonstrate that IR cell irradiation can be used to perform simultaneous ablation and labeling of cells in the same embryo. I use this system to uncover a role for the …