Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"dLGN"”.
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Circuit Development in the Dorsal Lateral Geniculate Nucleus (dLGN) of the Mouse.
… and the dorsal lateral geniculate nucleus (dLGN) of the mouse has emerged as a model for investigating the cellular and molecular mechanisms underlying the development and activity-dependent refinement of sensory connections. Thalamic organization is highly conserved throughout species and …
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Mechanisms underlying retinogeniculate synapse formation in mouse visual thalamus
… cells of the dorsal lateral geniculate nucleus (dLGN). They are critical for regulating the flow of visual information from retina to primary visual cortex (V1). RG synapses in dLGN are uniquely larger and stronger than their counterparts in other retinorecipient regions. Moreover, in dLGN, RG …
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DEVELOPMENTAL REMODELING OF RELAY CELLS IN THE DORSAL LATERAL GENICULATE NUCLEUS (dLGN) OF THE MOUSE AND THE ROLE OF RETINAL INNERVATION
The dorsal lateral geniculate nucleus (dLGN) has become an important model for studying many aspects of visual system development. To date, studies have focused on the development of retinal projections and the role of activity in shaping the pattern of synaptic connections made with …
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Postnatal development of brainstem cholinergic inputs to the dorsal lateral geniculate nucleus of the domesticated ferret, Mustela putorius furo
The ferret dorsal lateral geniculate nucleus (dLGN) undergoes two periods of retinal afferent segregation during postnatal development. The first establishes the eye-specific laminae, A and A 1, and the second establishes ON/OFF sublaminae within laminae A and At. In contrast to eyespecific …
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Investigating the role of thalamic activity in visual cortical plasticity
… analyzing the dorsal lateral geniculate nucleus (dLGN) of the thalamus, which is the primary source of visual information for the cortex. In the following sections, we test the hypothesis that SRP expression is driven by the mode of activity of dLGN neurons, which are in turn driven by feedback …
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Cells, circuits, and development of the mouse lateral geniculate nucleus
… regions: ventral LGN (vLGN), dorsal LGN (dLGN), and the intergeniculate leaflet (IGL). Previous studies have characterized the cytoarchitecture and circuitry of dLGN, which is crucial for classical image-forming vision. However, the molecular resolution of subtypes and the connection …
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Neuromodulation of Inhibitory Activity in Thalamocortical Circuits
… of miniature ISPCs (mIPSCs) recorded in dLGN relay neurons have greater variance than those recorded in ventrobasal nucleus (VB) neurons. It is important to note that in rodents, the dLGN has local interneurons (F1 & F2 inputs) whereas VB does not contain interneurons and thus lack F2 …
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LGN activity patterns during ocular dominance plasticity in vivo
… through the dorsal lateral geniculate nucleus (dLGN) of the thalamus and then into visual cortex. Several models of the thalamic activity patterns which drive OD plasticity have been proposed, but the assumptions about the pattern and amount of input activity from thalamus to cortex during …
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The Role of Synaptically Evoked Plateau Potentials in Retinogeniculate Development
… cells in the dorsal lateral geniculate nucleus (dLGN) of the thalamus and are reportedly needed to help guide the segregation of retinal inputs into eye-specific domains as well as for the pruning of extraneous retinal inputs onto single dLGN relay cells. The composition of retinally evoked …
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MELANOPSIN AND PACAP IN INTRINSICALLY PHOTOSENSITIVE RETINAL GANGLION CELLS REGULATE THE DEVELOPMENT OF RETINOFUGAL PROJECTIONS IN MICE
… in the dorsal lateral geniculate nucleus (dLGN) have not been extensively determined. To answer these questions, I used tract tracing with eye injections and mesoscale imaging to assess ipRGC projections to the SCN and dLGN of both juvenile melanopsin (Opn4cre/cre) and conditional …
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Three Dimensional Organisation of the Adult Mouse dorsal Lateral Geniculate Nucleus
The dLGN (dorsal Lateral Geniculate Nucleus) is the gateway to cortical processing for visual information encoded by RGCs (retinal ganglion cells). Owing to advances in genetic manipulations, the mouse is increasingly the model system of choice for understanding the function and organisation of the …
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The development, cytoarchitecture, and circuitry of the ventral lateral geniculate nucleus
… input are the dorsal lateral geniculate nucleus (dLGN) and ventral lateral geniculate nucleus (vLGN), both of which reside in the thalamus. The dLGN is well-studied and known to be important for classical image‐forming vision. The vLGN, on the other hand, is associated with non‐image‐forming …
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Characterization of the Role of R7-RGS Proteins in Mammalian Retina and Vision
… in the dorsal lateral geniculate nucleus (dLGN), iii) characterization of blockade of RGS regulation of Gi2 and Go subunits on outer retina function, and iv) preliminary analysis of the effect of RGS6 ablation on vision. In part i), we found that R7BP is expressed in starburst amacrine …
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The Albino Mouse Visual System: How Perturbed Retinal Development Leads to Altered Binocular Projections
… in the dorsal lateral geniculate nucleus (dLGN) of the mouse, suggestive of misspecification of RGCs in this region. Further, as revealed by expression of Islet1/2 as a marker of differentiated RGCs, the number of differentiated RGCs in the VT retina is lower in the albino compared to …