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Showing 1 to 2 of 2 for “"dHSC"”.

  1. Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei

    … divergent paralogs of DHS (DHSp: Tb927.1.870 and DHSc: Tb927.10.2580), only one of which (DHSc) contains the key catalytic lysine. I showed that both DHS genes are essential for growth of bloodstream-form T. brucei using conditional gene knockouts, further establishing the requirement for …

    utswmed Repository record for Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei (opens in a new tab)

  2. The Role of Gata3 in Blood Stem Cell Emergence

    The first definitive haematopoietic stem cells (HSCs) produced during embryonic development are generated from a specialised subset of endothelial cells known as haemogenic endothelium. Recently, it was reported that Gata3 plays a dual role in the development of sympathetic nervous system and …

    cambridge Repository record for The Role of Gata3 in Blood Stem Cell Emergence (opens in a new tab)