Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"cytotoxity"”.
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Synthesis and cytotoxity of oxysterols:studies on the A,B ring polyoxygenated sterols
Oxysterols (OS), the polyoxygenated sterols, represent a class of potent regulatory molecules for important biological actions. Cytotoxicity of OS is one of the most important aspects in studies of OS bioactivities. However, studies, the structure-activity relationship (SAR) study in particular, …
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rRNA transcription as potential therapeutic target in triple negative breast cancers
… as RNAP1 inhibitor, is characterized by low cytotoxity and very high anti-cancer effect. However, the exact molecular mechanisms of RNAP1 inhibition is unknown. Therefore, this experiment aims to identify the stage of the transcription cycle affected by PMR-116 by using a combination in vitro …
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The evaluation of targeted radionuclide therapies and radio sensitising agents in malignant melanoma
… X-ray irradiation. Novel IKKβ inhibitors induce cytotoxity and enhance 1GY Xr-ray [sic] toxicity compared to X-ray treatment alone.
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The Effects of Discharge Nursing Intervention Program On the Self-care for The Elderly with Cancer
… are also increasing. Because of the aspecific cytotoxity of anticancer drugs, which is one method of treating cancer, the patients have a very hard time while receiving the chemotherapy. Thus, they are in absolute need for nurses' intervention regarding follow-ups which can improve the …
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The role of Ryanodine receptors in neuronal calcium signaling
… high levels of gene knockdown and its low cytotoxity, our result suggests that siRNA silencing for RyRs may become a promising gene therapeutic target in the future.
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Molecular cloning, structural characterisation and functional study of peptides from amphibian skin secretion
… The three short peptides showed low cytotoxity against horse blood erythrocytes and cancer cells. Moreover, QUB1457 also showed a rapid time-killing ability against MRSA. The membrane permeability results revealed that QUB1361, QUB1274 and QUB1457 demonstrated outer membrane and inner …
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An inventory and pharmacological evaluation of medicinal plants used as anti-diabetes and anti-arthritis in Vhembe District Municipality, Limpopo Province
Diabetes and arthritis are the most common chronic diseases. Arthritis is the leading cause of global disability and diabetes has become a major health problem which is increasing rapidly. The purpose of the study was to document medicinal plants that are used to treat and manage diabetes and …
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Selection and evaluation of ten medicinal plants used, in the Vhembe District, for life-threatening infections
See the attached abstract below
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Synthetic studies and biological evaluation of chromone - 3 - carbaldehydes
Chromones are well known naturally occurring heterocyclic compounds with oxygen as a heteroatom. Chromones are also one of the major classes of naturally occurring compounds, and the interest in their chemistry is due to their wide range of their biological activity. In this study, three classes of …