Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 625 for “"cytoskeleton"”.
-
Membrane-cytoskeleton associations during myogenesis
… interactions between the cell surface and cytoskeleton in developing muscle. To examine this possibility, plasma membrane-cytoskeleton associations involving specific membrane proteins were studied in developing L8E63 cells on the basis of the following criteria: Triton-insolubility, …
-
Regulation of the Cytoskeleton by Kinesins
… KIF2C, and KIF24. These proteins regulate the cytoskeleton through their microtubule depolymerizing activity. All four kinesins have reported functions in mitosis, while little is known about their roles in interphase. KIF2A and KIF2C are upregulated in cancer cells and the increased protein …
-
Mechanical Regulation of Glycolysis via Cytoskeleton Architecture
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
-
Morphology and Mechanics of the Actin Cytoskeleton
… form and mechanics of part of the cellular cytoskeleton known as the lamellipodium. The cellular cytoskeleton is made of filamentous proteins, such as F-actin, and provides for structural support for the cell. Lamellipodia are extensions of the cellular cytoskeleton at the leading edge of a …
-
The plant cytoskeleton as a transportation network
The cytoskeleton is an essential component of living cells. It is composed of different types of protein filaments that form complex, dynamically rearranging, and interconnected networks. The cytoskeleton serves a multitude of cellular functions which further depend on the cell context. In animal …
-
Simulation of actin cytoskeleton structure and rheology
… major structural component in cortex is actin cytoskeleton. Thus, understanding the origin of viscoelasticity of cross-linked networks should be crucial to figure out the exact role of cytoskeletal behaviors in many cellular functions. Here, we introduce a Brownian dynamics (BD) simulation …
-
P21- ACTIVATED KINASE 4 AND ACTIN CYTOSKELETON DYNAMICS
P21-ACTIVATED KINASE 4 (PAK4), A SERINE/THREONINE KINASE FROM THE GROUP II PAK FAMILY KINASES, IS ONE OF MANY ACTIN DYNAMICS REGULATORS THAT CONTROL THE FORMATION OF ACTIN-RICH STRUCTURES SUCH AS FILOPODIA IN MAMMALIAN CELLS. PAK4 PHOSPHORYLATES LIM KINASE (LIMK), WHICH IN TURN, PHOSPHORYLATES THE …
-
Organization of Postsynaptic Proteins via the Neuronal Cytoskeleton
… cultures to test directly the role of the cytoskeleton in localizing neurotransmitter receptors, and potential anchoring and signal transducing proteins at postsynaptic sites. Neurons were treated with latrunculin A to depolymerize actin, vincristine to depolymerize microtubules, or Triton …
-
Adhesion receptor-cytoskeleton interactions in migrating tissue cells
… an available fibroblast system in which the cytoskeleton-binding domain of integrin was altered by site-directed mutagenesis. Three distinct approaches were taken: (1) laser optical trapping and nanometer-precision tracking were utilized to investigate the dynamics of integrin-cytoskeleton …
-
Function of Spectrin cytoskeleton in regulating epithelial architecture.
… component of both apical and lateral Spectrin cytoskeletons, the study was mainly focused on α-Spec. The study showed that α-Spec and β-Spec are essential in maintaining a mono-layered FE, but, contrary to previous reports, Spectrins are not required to control proliferation. Furthermore, loss …
-
Crosstalk between CX3CL1 and the Cytoskeleton during Vascular Inflammation
The ability of the cortical actin cytoskeleton to regulate the lateral diffusion of plasma membrane molecules is a fundamental guiding principle underlying many cellular processes. By creating and stabilizing diffusional barriers, the cytoskeleton can precisely regulate the association or …
-
Interactions between the plant Golgi apparatus and the cytoskeleton
… the relationship between the Golgi apparatus and cytoskeleton has been well characterised but not much is known in plants. The functions of the Golgi apparatus are conserved amongst eukaryotes. It is one of the main stations in the secretory pathway and is involved in protein processing and …
-
Mechanisms of Regulation of Mitochondrial Dynamics by the Actin Cytoskeleton
… of mitochondrial dynamics by the actin cytoskeleton. First, we examined actin’s influence over equivalent mitochondrial partitioning between daughter cells in mitosis. Propagating in the space surrounding mitochondria is a wave of actin polymerization and depolymerization. In control and …
-
Submembrane cytoskeleton-regulated assembly and functional activity of gap junctions
Connexine formen gap junctions, die den Transfer von Ionen, Metaboliten und second messengers zwischen sich berührenden Zellen vermitteln. An vielen Funktionen der Connexine, z.B. zellulärer Transport, Plaquebildung und -stabilität sowie Kanalleitfähigkeit sind Proteine beteiligt, die an die …
-
Three dimensional reconstruction of the cell cytoskeleton from stereo images
… study examines 3D reconstruction of the cell cytoskeleton. This application of stereo vision to electron micrographs extracts information about the interior structure of cells at the nanometer scale level. We propose two different types of stereo vision approaches: the line-segment and wavelet …
-
3D reconstruction from 2D images and applications to cell cytoskeleton
… is given to the reconstruction of the cell cytoskeleton from electron microscope images. The thesis is composed of two parts. The first part studies computer-vision-based reconstruction methods that extract 3D information from geometric relationship among images. First, a …
-
Regulation of the actin cytoskeleton in the neuronal growth cone
… singling pathways leads to changes in the cytoskeleton of the growth cone that affect its motility. Although a number of the key players in this system have been identified, the means by which the growth cone is able to directly rearrange its cytoskeleton in response to guidance cues is not …
-
Anillin Stabilizes Membrane-cytoskeleton Interactions During Drosophila Male Germ Cell Cytokinesis
The scaffolding protein anillin plays a crucial role during cytokinesis – the physical separation of daughter cells following chromosome segregation. Anillin binds filamentous F-actin, non-muscle myosin II and septins, and in cell culture models has been shown to restrict actomyosin contractility …
Page 1 of 32