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Showing 1 to 1 of 1 for “"cytoplasmic cyclin E"”.
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Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors In Breast Cancer
… of such resistance is not completely understood. Cyclin E is deregulated in breast cancer through generation of low molecular weight isoforms that renders patients to a poor survival. Herein, we show that HR+ patients with LMW-E expressing tumors show diminished early response to neo-adjuvant AIs …