Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 38 for “"cytoplasmic and nuclear"”.
-
Characterization and Functional Analysis of the Arabidopsis Intron Splicing Factor ASF/SF2
… assay demonstrate RNA binding ability of SF2a and RRM domain, but not SF2b protein. Immunostaining of TN-5 cells expressing recombinant proteins and western blot analyzing cytoplasmic and nuclear fractions of expression cells showed targeting of SF2a, SF2b and their SR domains to the nuclei. SR …
-
Cyclic AMP and the Induction of Reactive Astrogliosis
… hypertrophy of their cellular processes and hyperplasia (proliferation), a process referred to as reactive astrocytosis. Reactive astrogliosis can be modeled in vitro using mechanical (scratch wound) or chemical stimuli to activate F98 rat glioblastoma cells from a quiescent state to a …
-
ΜΗΧΑΝΙΣΜΟΙ ΠΟΥ ΕΛΕΓΧΟΥΝ ΤΗΝ ΑΡΡΕΝΩΠΟΤΗΤΑ (ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ ΣΕ ΔΥΟ ΣΤΕΛΕΧΗ ΠΟΝΤΙΚΩΝ)
… BY LIMITED CAPACITY UPTAKE SYSTEMS IN CYTOPLASM AND NUCLEUS, WHICH REPRESENT CYTOPLASMIC AND NUCLEAR RECEPTORS RESPECTIVELY. THE CAPACITY OF UPTAKE SYSTEMS IS THE SAME, WHILE THE EFFICIENCY IS GREATER IN C57 THAN IN DBA. INTHE HYPOTHALAMUS, TESTOSTERONE IS METABOLIZED IN BOTH STRAINS TO 5A …
-
Effects of selenite on metabolic events during the proliferation of canine mammary tumor cells
Increased cytoplasmic and nuclear selenium retention in CMT-13 cells was correlated with cell growth inhibition caused by selenite supplementation. Greater quantities of cytosolic selenium-containing proteins and a nuclear selenium-containing protein were detected as the quantity of selenium within …
-
Nherf1 – New Modifier of Colorectal Cancer Progression
… specimens for changes in NHERF1 expression, and modeled these changes in two- and three-dimensional (2D and 3D) Caco-2 CRC cell systems. NHERF1 had significant alterations from normal to adenoma and carcinoma transitions (2=38.5, d.f.=4, P<0.001), displaying apical membrane localization in …
-
The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner
… αCT1, originally designed to bind to ZO1 and thereby inhibit Cx43/ZO1 interaction, was used as a tool to probe the role of Cx43/ZO1 association in regulation of epithelial/endothelial barrier function. Using both in vitro and ex vivo methods of barrier function measurement, including …
-
LNCFOXP3 CONTROLS CELL IDENTITY AND FUNCTION OF HUMAN REGULATORY T CELLS
… playing crucial roles both in physiological and pathological contexts. Treg suppressive activity correlates with the tightly regulated expression and stability of their master transcription factor FOXP3. Given the role of lncRNAs in defining cell identity and function, we have previously …
-
Mechanisms of multidrug resistance in bladder cancer: the role of the nuclear membrane
… (ABC) transporter proteins, cytoplasmic vaults, alterations in<br/>topoisomerase II and increased expression of glutathione-S-transferases, all of<br/>which result in reduced chemotherapeutic efficacy.<br/><br/>Superficial bladder cancer is commonly treated with adjuvant …
-
The Domains of The Catalytic Subunit of The Eukaryotic Rna Degrading Exosome, Rrp44P, Have Distinct Functions
… degrades mRNA in a general mRNA turnover pathway and in several mRNA surveillance pathways. In the nucleus, the exosome processes RNA precursors to form small, stable, mature RNA species, including rRNA, snRNA, and snoRNA. In addition to processing these RNAs, the nuclear exosome is also involved …
-
Characterization of Pituitary Protein Expression Patterns During Stages in the Reproductive Cycle of Turkey Hens
… turkey hens in the egg-laying (LAY) stage and produce one additional egg per hen a year is estimated to save the turkey industry approximately $1.5 million dollars per year. Overall protein expression generated by tissues of the hypothalamic-hypophyseal complex, namely the anterior …
-
Androgen aromatization and cytosol estradiol-receptors in the mediation of masculine sexual behavior in Japanese quail
… tissues from functionally castrated, High (HM) and Low Mating (LM) line quail to compare (1) the in vivo aromatization of ³H-testosterone and (2) cytosolic estradiol-binding by in vitro saturation analyses. After in vivo incubation with ³H-testosterone, all radioactivity recovered in brain …
-
Nuclear and cytoplasmic genetic variation in Picea: DNA markers for evaluating past migration, introgression and evolutionary history
<p>Mitochondrial and chloroplast haplotypes were identified in range-wide populations of white (Picea glauca), black (P. mariana ) and red spruce (P. rubens). The chloroplast genome exhibited more intraspecific variation than the mitochondrial genome. Red spruce displayed the most total chloroplast …
-
Study of the role of plant nuclear envelope and lamina-like components in nuclear and chromatin organisation using 3D imaging
The linker of nucleoskeleton and cytoskeleton (LINC) complex is an evolutionarily well-conserved protein bridge connecting the cytoplasmic and nuclear compartments across the nuclear membrane. While recent data supports its function in nuclear morphology and meiosis, its implication for chromatin …
-
Biological Functions of Intracellular Hepatitis B e Antigen
… from core in its inability to form a capsid and the biological functions of cytoplasmic and nuclear p22. Firstly, we have identified that a portion of p22, after the cleavage of its signal peptide in ER, is released back into the cytosol through an ERAD-independent mechanism, as neither …
-
The identification of prostate cancer associated tumour antigens and biomarkers
… (PSA) testing has resulted in the over detection and over treatment of potentially indolent disease due to the lack of specificity of PSA for prostate cancer (PCa). PROTEOMEX, a method of tumour associated antigen (TAA) identification, combines the separation of tumour proteins by conventional …
-
The role of FOXK transcription factors in Wnt signal transduction
… including patterning during embryogenesis and stem cell homeostasis in the adult organism. Wnt signals are received at the cell membrane and transduced through cytoplasmic and nuclear multiprotein complexes; the degradasome, signalosome and enhanceosome. The latter is tethered to enhancers …
-
Restriction fragment length polymorphism analysis of chloroplast DNA, mitochondrial DNA, and ribosomal DNA in turfgrasses
… DNA (cpDNA), mitochondrial DNA (mtDNA), and ribosomal DNA (rDNA), were used to estimate and compare the extent of diversity among the organellar and nuclear genomes, and to infer species relationships. Eight cultivated turfgrass species and subspecies were used in this study including: …
-
Investigation of Transcriptional Regulation of 5'-Nucleotidase in Dictyostelium Discoideum
… in Dictyostelium discoideum between the prestalk and prespore zones. This enzyme is referred as 5'-Nucleotidase (5NT). Given the critical role of cyclic AMP in cell differentiation in this organism, 5NT is thought to be involved in cell positioning during development. Southern blot analysis showed …
-
Investigating the Role of the IP₃ Signalling Pathway in RNA Interference in C. elegans
… 1,4,5-trisphosphate (IP₃) mediated signalling and RNA interference are widespread processes with fundamental roles in animal cell function. In the nematode C. elegans these two pathways have been shown to intersect such that IP₃ signalling mutants display an altered exogenous RNAi response. IP₃ …
-
Identification of Ligands for the Orphan Nuclear Receptor DAF-12 That Govern Dauer Formation and Reproduction in C. Elegans
The orphan nuclear hormone receptor, DAF-12, plays a central role in the physiology of free-living nematode, C. elegans. DAF-12 is best known for its role in regulating dauer formation, a non-reproductive larval state entered in harsh environments and marked by developmental arrest, stress …
Page 1 of 2