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Showing 1 to 1 of 1 for “"cytokine-independent self-renewal"”.
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Cryo-electron microscopy studies of pluripotency factor Nanog
… These cells are characterised by the ability to self-renew and to give rise to cell types from all lineages, known as pluripotency. Culture of ES cells in vitro requires addition of signalling molecules such as LIF to block differentiation signals and maintain self-renewal. At the transcriptional …