Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"cytokine inhibitor"”.
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The role of oxygen free radicals in the endotoxic shock induced myocardial dysfunction and cellular injury
… (ET-shock) associated with increased levels of cytokines (interleukin-1 (IL-1) and tumour necrosis factor (TNF)), platelet activating factor (PAF), activated complement (C3a, C5a) and norepinephrine in the blood. Activated complement, IL-1, TNF and PAF are known to activate polymorphonuclear …
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Circadian Disruption by Light at Night: Implications for Mood
… report that administration of a pharmacological cytokine inhibitor prevents depressive-like behaviors in LAN, implicating brain inflammation in the behavioral effect. Finally, I demonstrate in Chapter 7 that exposure to red wavelength LAN reduces the effects on brain and behavior, suggesting that …
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A Characterisation and Understanding of the Germinal Centre B Cell Response to Atherosclerosis in Mice using Lineage Tracing
… inflammation separately. Use of a cholesterol inhibitor drug and cholesterol free diet revealed that dietary cholesterol is key in driving the exacerbated germinal centre responses observed at early stages i.e., 4 weeks of atherosclerosis. Use of a cytokine inhibitor to dampen inflammation …
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Herstellung und Charakterisierung hochaffiner Inhibitoren für die Zytokine IL-6 und LIF basierend auf den Liganden-bindenden Domänen ihrer Rezeptor-Untereinheiten
Cytokines are small secreted proteins produced by different cell types in nearly all tissues. They are used as intercellular mediators being involved in the regulation of immunity and inflammation. Dysregulated cytokine production plays an important role in the development and progression of …