Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 62 for “"cytokeratin"”.
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The Significance of Cleaved Cytokeratin 18 in Pleural effusion
… 검사를 시행하였고 상피세포의 사멸을 평가하기 위하여 caspase-cleaved cytokeratin 18의 특이적 항원인 M30에 대한 항체를 이용하여 혈청 및 흉수에서 ELISA를 시행하였고 흉막 조직에서 면역조직화학염색을 시행하여 분석하였다. 결과 : 흉수 내 M30의 농도는 결핵 (2632.1 ± 1467.3 U/mL)에서 폐암 (956.5 ± 618.5 U/mL), 폐렴 (689.9 ± 413.6 U/mL), 심부전 (273.6 ± 144.5 U/mL; p < 0.01)보다 유의하게 높았다. 혈청 내 M30의 …
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Serum Specific IgG to Cytokeratin : A Useful Serologic Marker for Toluene Diisocyanate-Induced Asthma
… of specific IgG to three major epithelial cytokeratins (CK)-CK8, CK18, and CK19-in 66 patients with TDI-induced asthma (group Ⅰ), compared with three control groups: 169 asymptomatic exposed subjects (group Ⅱ), 64 patients with allergic asthma (group Ⅲ), and 123 unexposed healthy control …
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Detection of Cytokeratin 19 and 20 in Portal Bloods in Right Colon Cancer Patients
… operations on 20 patients with colon cancer. Cytokeratin(CK) 19 and 20 transcripts were amplified using a reverse trascriptase-PCR assay. As a negative control, 10ml of portal blood from 10 patients who underwent benign surgery were assayed. The HCT-116 colon cancer cell line was used for the …
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Caspase-cleaved fragments of cytokeratin-18 as a marker of inflammatory activity in chronic hepatitis B virus infection
… chronic hepatitis B (CHB) virus infection. Serum cytokeratin (CK)-18 fragments (M30 antigen) are proposed as biomarkers of apoptosis. We investigated whether serum M30 levels might help to characterize the various phases of CHB and predict the state of significant inflammation in patients with …
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Developing a model to assess the contribution of cytokeratin 19-expressing cells during multipotent stromal cell-induced islet regeneration
Previously, pharmacological activation of Wnt-signaling in human bone marrow-derived multipotent stromal cells (hMSC) generated conditioned media (CM) that promoted β-cell regeneration in streptozotocin-treated mice. Ductal-derived endocrine progenitors, which have been shown to generate β-cells …
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Prognostic Value of Bone Marrow Micrometastasis Detected by Nnested RT-PCR for Cytokeratin 19 and Mammaglobin in Breast Cancer
… Seventy-five out of 250samples were studied cytokeratin 19 and others were studied cytokeratin and mammaglobin. Median follow-up time was 21.1 months. Sixty-five(26%) out of 250 samples were cytokeratin 19 positive and 25 (14.3%) out of 175 were mammaglobin positive. Eight cases (12.3%) in …
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Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
… markers were assessed. Human markers included cytokeratin 1,cytokeratin 5, cytokeratin 13, cytokeratin 14, collagen type IV, laminin, elastin, fibronectin,Langerhans cells and VEGFR-3. Murine markers included collagen type IV, laminin,fibronectin, Langerhans cells and VEGFR-2. Staining …
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Efeito do fumo na expressão proteica da citoqueratina 19 (k19) em células epiteliais da mucosa bucal
Objective: to compare the expression of cytokeratin 19 (K19) in epithelial cells of the oral mucosa of smokers, nonsmokers and former smokers. Methods: samples of epithelium of the oral mucosa of smokers (n=20), non-smokers (n=20) and former smokers (n=20) were collected by mouthwash and processed …
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Zur funktionellen Architektur des Nukleolus in lebenden Zellen
… wurden die Antigene überraschenderweise als Cytokeratin-Homologe identifiziert. Im Verlauf dieser Arbeit wurden drei bisher unveröffentlichte Cytokeratin 19 Isoformen von Xenopus kloniert, sequenziert und als GFP-Fusionsproteine exprimiert. Diese wurden allerdings wie reguläre Cytokeratine in …
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Zytologie und Immunozytochemie von Mesothelzellen im Ergüssen
… umfaßte die mesotheltypischen Marker Calretinin, Cytokeratin und Vimentin, einen Antikörper gegen das von Mesothelzellen nicht exprimierten CEA-Antigens, den makrophagenspezifischen Marker CD68 und einen Antikörper zum Nachweis einer Proliferationsaktivität (MIB-1). Die Auswertung erfolgte zum …
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Investigation of respiratory surfactant A protein in middle ear epithelium
… to identify surfactant A protein as well as four cytokeratins expressed in lung cells. Results: We have demonstrated that surfactant protein A is indeed expressed in the middle ear and that there are cells which have a protein cytokeratin expression consistent with surfactant production and other …
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COMPARATIVE PROTEOMICS STUDIES OF SOLUBLE NUCLEAR PROTEINS OF DRUG SUSCEPTIBLE AND RESISTANT HUMAN BREAST CANCER MCF-7 CELLS
… Abundances of cytoskeleton proteins, such as cytokeratin 8, cytokeratin 19, septin 2, and alpha tropomyosin, are altered in common across the three resistant cell lines. MCF-7 cell lines resistant to etoposide and mitoxantrone are more similar in protein abundance changes. Some of the proteins …
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IMMUNOPROFILE IN EFFUSION CYTOLOGY
… were stained with a standard panel of Vimentin, Cytokeratin (CK) AE1/AE3, CK 5/6 and HBME‐1 as mesothelial cell markers; desmin as mesothelial cell malignancy marker; and CK7/CK20 as a marker of metastasis. Malignancy was confirmed by histologic evaluation; non‐malignant conditions were confirmed …
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An Immunochemical Analysis of Alcoholic Hyaline and its Relationship to Keratin Intermediate Filaments
… corneum keratin (HSCK) and normal human liver cytokeratin (HCK) by quantitative immunochemical means, using polyclonal as well as monoclonal antibodies. Enzyme-linked immunosorbent assays (ELISAs) were employed, as well as "immunoblotting" and immunocytochemical techniques. HCK was isolated …
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Biomarker development for gastrointestinal and ovarian cancer: a proteomic approach
… index, lymphovascular invasion and tumour stage. Cytokeratin 18 (CK18) is an epithelial-specific cytokeratin that undergoes cleavage by caspases during apoptosis. Measurement of caspase-cleaved (CK18-NE) or total cytokeratin 18 (CK18) from epithelial-derived tumours could be a simple, non-invasive …
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DEVELOPMENT OF IN VITRO NON-ALCOHOLIC STEATOHEPATITIS (NASH) MODEL FOR DRUG TESTING AND PATHOGENESIS STUDIES
… observed in in vivo settings. We recognized cytokeratin 18 fragment (M30) as a quantifiable biomarker for hepatocellular ballooning, which positively correlated with the level of steatosis and inflammation. ScRNA-seq was performed to find the ballooned hepatocyte cluster. An AMPK signalling …
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Changes in serum histologic surrogate markers and procollagen III N- terminal peptide as independent predictors of HBeAg loss in patients with chronic hepatitis B during entecavir therapy
… (PIIINP) and TIMP1, MMP2, hyaluronic acid and cytokeratin 18 fragment levels were significantly decreased and the haptoglobin level was significantly increased from baseline after entecavir treatment. Multivariate analysis identified PIIINP (P=0.028) and the initial virologic response (P=0.019) …
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Ανοσοϊστοχημική μελέτη του πλακούντα με ιδιαίτερη έμφαση στα κύτταρα Hofbauer
… syncytiotrophoblast showed positive staining for Cytokeratin at all of the three trimester of pregnancy, for EMA only in the third trimester and for a1-AcT and a1-AT in the first trimester. It was consistently unreactive with any of the other antigens employed in the present study. 5. Positive …
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Magnesium-induzierte Apoptose im Trophoblasten
… apoptosis was evaluated by tissue morphology, cytokeratin-18 neoepitope formation in immunohistochemistry and Western blotting, TUNEL-Test and DNA-Laddering. RESULTS: Magnesium stimulated a concentration- and time-dependent placental apoptosis. In particular magnesium concentrations over 0.7 mM …
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Avaliação da expressão de citoqueratinas na citologia esfoliativa da mucosa bucal de pacientes fumantes
The present study compared the expression of cytokeratins CK6, CK16 and CK19 and pan-cytokeratin (PAN) in oral mucosa cells between smokers and nonsmokers in order to determine the stage of cell differentiation and to consequently infer proliferative activity and expressions indicative of a …
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