Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"cytogenetic analysis"”.
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Cytogenetic Analysis Of Depleted Uranium Exposure And Age-Dependent Susceptibility To Ionizing Radiation
… relationships were observed between any cytogenetic endpoint and log(urine Uranium) levels, smoking, or log(lifetime X-rays). Age at the time of blood draw showed significant relationships with all endpoints except for cells with acentric fragments. These results indicate that chronic …
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Molecular-cytogenetic analysis of repetitive sequences in genomes of Beta species and hybrids
… work presents the molecular investigation and cytogenetic characterization by high-resolution multicolor fluorescent in situ hybridization (FISH) of the satellite and dispersed repetitive sequences in wild and cultivated beet species and in their hybrids. New repetitive sequences were isolated …
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A Cytogenetic and Karyotypic Study of Eighty-Seven Patients Clinically Diagnosed as Having Down's Syndrome at Woodward State Hospital
… Down's syndrome were studied by chromosome analysis at Woodward State Hospital, Woodward, Iowa, during June and July of 1972. Procedure. A cytogenetic analysis was made on chromosomes prepared from leucocytes cultured from peripheral blood. Ten cells were counted and karyotypes prepared for …
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Novel genomic technologies and molecular diagnostics in Colorectal Cancer
… 6.0) and two new tools were implemented, Broad Cytogenetic Analysis (BroCyA) and Focal Cytogenetic Analysis (FoCyA), to identify broad (> 1⁄4 chromosomal arm) and focal aberrations (< 1⁄4 chromosomal arm). Broad copy number gains were noted on chromosomes 7, 8q, 9, 13q, 17q, 20 and broad copy …
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Karyotypes and Case Studies of 17 Down's Syndrome Individuals
… Down's syndrome were studied by chromosome analysis at Woodward State Hospital, Woodward, Iowa during June and July of 1973. Procedure. A cytogenetic analysis was made of chromosomes prepared from leucocyte cultures from peripheral blood. At least 30-50 cells were counted and karyotypes made …
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Mechanisms and Consequences of Chromosomal Instability in Malignant tumours
… and multicolour FISH, a high resolution for cytogenetic analysis of tumours with chromosomal instability could be obtained. This combined approached was used also to search for reciprocal translocations leading to fusion genes in Wilms tumour. Although the technique proved efficient, no …
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Cytogenetic and Molecular Cytogenetic Markers in Patients with Multiple Myeloma - Prognostic Significance // Цитогенетични и молекулярно-цитогенетични маркери при пациенти с множествен миелом – прогностично значение
… Marina University Hospital – Varna. Conventional cytogenetic analysis was performed at diagnosis in 97 of the patients. It was successful in 83 of them, and in 14, no metaphases were found for analysis despite culture. Of the 83 successfully performed analyses, the karyotype was normal in 69 and …
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The Relationship Between Satellite Association and Trisomy 'G'
… production of such. The literature covering the cytogenetics and technical significance of satellite association, together with the clinical, cytogenetical, and parental age involvement in trisomy 'G', has been reviewed. The design of this investigation was divided into two parts, namely …
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Biological and functional consequences of polymorphisms in the XPD gene
… chromosomal aberrations (Ca) were assessed by cytogenetic analysis and then P values were calculated as estimates of sub-population differences for increased frequencies of CAs associated with the three XPD polymorphisms. I found significant elevation in baseline frequencies of CAs among …
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The genetic and molecular analysis of the mfs(2)31 locus in Drosophila melanogaster : a novel suppressor of position-effect variegation
… by one such recessive mutation, mfs(2)31. A cytogenetic analysis of subdivisions 31D-E was undertaken to determine the precise location of the mfs(2)31 locus and to isolate additional alleles. Five new deficiencies and 123 new lethal mutations were induced, allowing for the partitioning of …
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Fusion genes in breast cancer
… under-reported due to the difficulties of cytogenetic analysis of solid tumours. In particular, breast cancers often have complex, highly rearranged karyotypes which have proved difficult to analyse using classical cytogenetic techniques. The aim of this project was to search for fusion …
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Studio citogenetico della famiglia Muraenidae (Anguilliformes: Actinopterygii) mediante tecniche di citogenetica classica e molecolare
… and genera is still controversial. Comparative cytogenetic, allowing the study of karyotype evolution among species and genera, could contribute to shed light on taxomomic and phylogenetic incertainties on Muraenidae family. Till now, less of 10% have been karyologically analysed and a very few …
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Die Bedeutung der Embryonenqualität im Rahmen des Embryotransfers beim Rind – eine Literaturstudie
… for the practical use of the embryo transfer. Cytogenetic analysis of embryos is an important issue for caryotyping. Chromosomal deviations are known to cause early embryonic mortality in cattle. Determination of the total cell number and the allocation of these cells to the inner cell mass …
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Developing novel SNAP tag-based antibody fusion proteins directionally conjugated to fluorophores for immunophenotyping of acute myeloid leukemia
… molecular genetic tests, including chromosomal analysis, next-generation sequencing, real-time polymerase chain reaction and cytogenetic analysis. Immunophenotyping by flow cytometry and immunohistochemistry can be used to identify specific proteins or antigens upregulated in AML. In low and …