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Showing 1 to 7 of 7 for “"cytochrome bc1 complex"”.
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Theoretical study of the cytochrome bc1 complex reaction mechanism
The bc1 complex is an enzyme which plays a critical role in energy production through photosynthesis and cellular respiration. Its biochemical function relies on the so-called Q- cycle, which is well established and operates via quinol substrates that bind the protein at their active sites. Despite …
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The Structure-Function Interface in the Cytochrome Bc1 Complex Family
Mitochondrial bc1 complexes and chloroplast b6f complexes belong to a common family of quinol oxidizing enzymes. We have made a systematic survey of the redox subunits of the bc-type quinol oxidases for all known bacterial sequences and have identified six new representatives of the enzyme. …
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Spectroscopic and Electrochemical Analysis of the Rieske Iron-Sulfur Protein of the Rhodobacter Sphaeroides Bc1 Complex
… protein (ISP) subunit of Rhodobacter sphaeroides cytochrome bc1 complex was isolated and then investigated using molecular spectroscopies (high-resolution electron paramagnetic resonance and resonance Raman), protein-film voltammetry, and x-ray crystallography. Major accomplishments include the …
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Identifying the mechanism of second proton release from the bc1 complex Qo-site
The cytochrome bc1 complex and its family members play a central role in biological energy transduction across all domains of life, oxidizing QH2 in a bifurcated reaction which generates a proton-motive force used for ATP synthesis. It is widely accepted to operate according to a modified Q-cycle, …
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Protein Coevolution and Coadaptation in the Vertebrate bc1 Complex
The cytochrome bc1 complex of the mitochondrial electron transport chain accomplishes the enzymatic reaction known as the modified Q-cycle. In the Q-cycle the bc1 complex transports protons from the matrix to the intermembrane space of the mitochondria, creating the proton gradient used to make …
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Steered molecular dynamics: a tool to investigate molecular interactions
… of one of the domains of the mitochondrial cytochrome bc1 complex controls the bifurcation of the electron transfer governing the energy transduction in the complex. A solvated structure of the complex in a phospholipid bilayer was modeled. The domain movement was induced in SMD simulations …
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Electron gating and mechanism of proton exit in quinol oxidation in cyt bc1 complex from R. sphaeroides
The cytochrome bc1 complex of Rhodobacter sphaeroides in wild-type and several strains mutated at the conserved -PEWY- glutamate residue (E272 in chicken, E295 in R. sphaeoroides) were characterized in situ to determine the functional role of this residue in the second electron transfer of quinol …