Global ETD Search

REGULATION OF ERK SIGNAL TRANSDUCTION BY SIGNAL-INDUCED CYSTEINE OXIDATION

Keyes, Jeremiah D.Wake Forest University2016

The ERK1/2 pathway plays roles across eukaryotic biology by transducing

wfu Repository record for REGULATION OF ERK SIGNAL TRANSDUCTION BY SIGNAL-INDUCED CYSTEINE OXIDATION (opens in a new tab)

LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF POST-TRANSLATIONAL MODIFICATIONS TO HMGB1 AND ITS REGULATED SECRETION IN LUNG CANCER

Gillespie , Kevin , Patrick2023

… modification (PTM), particularly acetylation and oxidation, mediate HMGB1 release and confer distinct extracellular HMGB1 signaling activity. However, the regulation of HMGB1 subcellular mobility in lung cancer by PTMs has not yet been established. To this end, a methodology was developed to …

penn Repository record for LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF POST-TRANSLATIONAL MODIFICATIONS TO HMGB1 AND ITS REGULATED SECRETION IN LUNG CANCER (opens in a new tab)

New tools for the discovery of pigment gene function

Adelmann, Charles H.Massachusetts Institute of Technology2021

… normal levels of cystine, the oxidized dimer of cysteine, in melanosomes, and to produce cysteinyldopas, the precursors of pheomelanin synthesis made in melanosomes via cysteine oxidation. Tracing and biochemical analyses show that MFSD12 is necessary for the import of cysteine into melanosomes, …

mit Repository record for New tools for the discovery of pigment gene function (opens in a new tab)

Functional significance of unique sequences in Mycobaterium smegmatis Ku proteins

Kushwaha, Ambuj KumarBiological Sciences2022

… event that stabilizes the protein and prevents cysteine oxidation, but has little effect on DNA binding. In vivo, zinc induced significant upregulation of the gene encoding Ku as well as a divergently oriented gene encoding a predicted zinc-dependent MarR family transcription factor. In …

lsu-thes Repository record for Functional significance of unique sequences in Mycobaterium smegmatis Ku proteins (opens in a new tab)

An investigation into the desensitization of neurotransmitter gated ion channels — functional relevance, impact on ganglionic receptor function, and structural insights

Papke, DavidUniversity of Illinois at Urbana-Champaign2013

… ganglia. Previously, it had been proposed that oxidation of an intracellular cysteine is fundamentally critical in the mechanism of this unusual desensitization; in the work presented in Chapter III, we found that this cysteine oxidation hypothesis cannot explain our results, implying that the …

uiuc Repository record for An investigation into the desensitization of neurotransmitter gated ion channels — functional relevance, impact on ganglionic receptor function, and structural insights (opens in a new tab)

Toward Engineering Oxygenase Activity into the Electron Transfer Protein Azurin

Sieracki, Nathan A.University of Illinois at Urbana-Champaign2011

… design, as precise knowledge and control of cysteine oxidation state is an important parameter in dictating function in cysteine-containing native and designed peptides and proteins. In Chapter 3, a series of Type-2 azurin variants is reported in which the anionic redox ‘chameleon’ Cys-112 is …

uiuc Repository record for Toward Engineering Oxygenase Activity into the Electron Transfer Protein Azurin (opens in a new tab)

Investigation of the Oxidation/Reduction of PRMT1, Substrate Interaction with PRMT1, and the Role of Arginine Methylation in RNA Surveillance

Nitzel, Damon V.

utahstate Repository record for Investigation of the Oxidation/Reduction of PRMT1, Substrate Interaction with PRMT1, and the Role of Arginine Methylation in RNA Surveillance (opens in a new tab)