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Showing 1 to 1 of 1 for “"cyclic oligoadenylate (cOA)"”.
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Identification and Characterization of Novel CRISPR-Cas Immune Effectors
… to type III CRISPR, is the synthesis of cyclic oligoadenylate molecules (cOAs) of various sizes from ATP substrates by the catalytic activity of the palm domain. cOAs go on to activate additional accessory immune effectors encoded within type III CRISPR loci that provide immunity …