Global ETD Search
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Showing 1 to 2 of 2 for “"cyclic nucleotide phosphodiesterases"”.
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Signalling to intracellular Ca2+ channels
… Ca$^{2+}$ signals. Inhibition of cyclic nucleotide phosphodiesterases with IBMX had no effect on the Ca$^{2+}$ signals evoked by carbachol after acute stimulation with PTH(1-34). However, during sustained stimulation (60 min), when cAMP levels were increased ~15-fold by IBMX, …
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Crosstalk Signaling Between cAMP and Calcium on the Leading Edge of Migrating Human Arterial Vascular Smooth Muscle Cells
… might limit these problems. Since the cyclic nucleotide phosphodiesterase, PDE1C, a dual cAMP/cGMP hydrolyzing PDE, is exclusively expressed by synthetic VSMCs and regulates their synthetic, migratory and proliferative actions, it may represent a valid synthetic VSMC specific …