Global ETD Search
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Showing 1 to 3 of 3 for “"cvt pathway"”.
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Isolation and characterization of Saccharomyces cerevisiae mutants for vacuolar import and autophagocytosis
… vacuole via the cytoplasm to vacuole trnasport (Cvt) pathway. The cytosolic protein is enclosed in a double-membrane vesicle, which is transported to and fuses with the vacuole releasing a single-membrane autophagic body into the vacuolar lumen. This is degraded and the precursor sequence of …
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Molecular analysis of vesicle biogenesis during autophagy
… Bre5 are also required for PMN but not for the Cvt-pathway or autophagy. The vps class E genes vps27 and vps28 are also exclusively required for PMN. So far the fusion of the edges of double-membrane structures leading to autophagosomes was dubious, since neither NSF / Sec18 nor t-SNARES are …
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Charakterisierung der Eaf 1-Funktion für die Biogenese der Aminopeptidase 1
… oligomerisiert, anschließend über den Cvt-Transportweg in die Vakuole transportiert und dort prozessiert. Die Isolierung und Charakterisierung zweier Mutanten via10 und via14 (vacuole import and autophagocytosis) mit reduzierter, bzw. keiner Ape1-Aktivität, sollte weitere Details über …