Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"cumulative incidence"”.
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Confidence Interval Estimation of Cumulative Incidence for Clustered Competing Risks
… occurring. Traditional methods of estimating the cumulative incidence for an outcome and its associated confidence interval under competing risks do not account for the effect of clustering. This may cause incorrect estimation of confidence intervals because outcomes among patients from the same …
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Risk of Subsequent Neoplasms During the Fifth and Sixth Decades of Life in the Childhood Cancer Survivor Study Cohort
… risk for subsequent neoplasms (SNs), but the incidence beyond age 40 and associations with therapeutic exposures have not been well- described. Among 14,364 childhood cancer survivors diagnosed between 1970 and 1986, 3,171 had an attained age ≥40 years at the time of last contact. Cumulative …
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Depression after stroke: natural history, predictors and associations with other health outcomes
… of post-stroke depression was conducted.<br/>Incidence, prevalence, cumulative incidence, time of onset, duration, and recurrence of depression, within 15 years of stroke were estimated in the population based South London Stroke Register (SLSR).<br/>Predictors and outcomes of depression up to …
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Natural History and Affecting Factors on Progression of Prehypertension and Prediabetes
… and health behaviors. RESULTS: The 8-year cumulative incidence rate of HTN in those with optimal, normal, and high-normal blood pressure (BP) was 175, 386 and 615 per 1,000 person-year respectively. In the Cox proportional hazard model, changes of CVD risk factors such as abstinence from …
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The Role of Meat, Poultry, and Fish Consumption in the Occurrence of Rheumatoid and Other Forms of Arthritis
… This dissertation measures the prevalence and cumulative incidence of rheumatoid arthritis and other forms of arthritis or rheumatism, and examines any associations with current and lifetime consumption of meat, poultry, and fish (meat) using the Adventist Health Study and the Adventist …
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Risk of Lower Extremity Amputation Revision in Patients with Peripheral Vascular Disease Adjusting for a Competing Risk of Death
… The aims of this study are to estimate the cumulative incidence of lower extremity amputation (LEA) revision and reamputation adjusting for a competing risk of death, estimate the one-year event-free mortality rates for patients with peripheral vascular disease undergoing LEA, and develop …
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PREVALENCE AND INCIDENCE OF HORMONAL-RELATED CANCERS (HRCs) IN RURAL SASKATCHEWAN: THE SASKATCHEWAN RURAL HEALTH STUDY
… residents. This study aimed to determine the incidence and prevalence of breast and prostate cancer among Saskatchewan rural dwellers and to explore individual and contextual factors that are associated with the prevalence of these cancers. To accomplish our goal, we utilized and analyzed data …
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Clinical Impact of A Highly Sensitive Next-Generation Sequencing Measurable Residual Disease Assay In Patients With Acute Lymphoblastic Leukemia
… and 23% of patients, respectively. The 5-year cumulative incidence of relapse (CIR) among patients who achieved MRD negativity by MFC at CR was 29%; in contrast, no patients who achieved MRD negativity by NGS at CR relapsed, and their 5-year OS was 90%. NGS MRD negativity at CR was associated …
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Five year rehospitalization outcomes in a cohort of acute ischemic stroke patients: medicare linkage study.
… dates. Kaplan-Meier survival curves estimated cumulative incidence rates. Cox regression models were used to calculate adjusted hazard ratios (HR) and confidence intervals (CI). Results Event rates and adjusted HR were: Mortality: 1 year SC=24%, NSC=4%; 5 years SC=49%, NSC= 24%; HR: 4.9 (95% CI …
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Targeting the human papillomavirus for prevention of cervical cancer
… studies of HPV-based cervical screening, the cumulative incidence rate of CIN grade 3 or worse (CIN 3+) was higher after 3 years among women with normal cytology than among women with a negative HPV test after 6 years. Finally, in a randomized cervical cancer screening trial in Sweden, adding …
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Primary cutaneous malignancies in the Northern Cape Province of South Africa: A retrospective histopathological review
… site and health sector were explored. One-year cumulative incidence was calculated and logistic regression models were used to analyse incidence and melanoma thickness trends. Results: 4270 biopsies (14 cutaneous malignancies) were identified. Most common were Squamous Cell Carcinoma (SCC), …
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Outcomes of infants starting Antiretroviral therapy in Southern Africa
… these outcomes. Competing Risk Analysis provides Cumulative Incidence Functions for mortality and programmatic outcomes. Multiple imputation was conducted and Rubin’s Rules provided pooled estimates from Survival Analysis.
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Effect of Human Immunodeficiency Virus Infection on Human Papillomavirus Clearance among Women in Senegal, West Africa
… HPV at baseline and during follow up. The 2-year cumulative incidence of clearance of type-specific HPV infection was estimated by Kaplan-Meier methods. Marginal Cox proportional hazards models stratified by incident/prevalent HPV infection were used to evaluate the effect of HIV status and type …
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Semiparametric Regression Under Left-Truncated and Interval-Censored Competing Risks Data and Missing Cause of Failure
… event types, known as competing risks. The cumulative incidence function (CIF) is a particularly useful parameter as it explicitly quantifies clinical prognosis. Common issues in competing risks data analysis on the CIF include interval censoring, missing event types, and left truncation. …
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Causal Inference with Survival Outcomes via Orthogonal Statistical Learning
… double/debiased machine learning estimators for cumulative weighted average treatment effects for both survival outcomes and competing risk outcomes. Our approach combines importance sampling, semiparametric theory, and Neyman orthogonality to resolve both model misspecification and lack of …
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Antidepressant Persistence Before and After the Introduction of Online Renewal
… online. Both the preliminary inspection of cumulative incidence curves as well as the supplementary analysis with the linear probability model corroborate the notion that online renewal is associated with lower renewal rates. A causal interpretation would be that online renewal had a modest …
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Detecting subclinical anthracycline therapy related cardiac dysfunction in low income country (SATRACD study)
… This PhD project aims to describe the incidence and predictors of subclinical ATRCD, assess the accuracy of simple echocardiographic parameters on detecting subclinical ATRCD and investigate the lipoprotein subfractions change after anthracycline therapy. Methods and results: Two …
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Risk of Cardiovascular Disease Inhibitors Among HIV seropositive Adults on Protease Inhibitors Containing Antiretroviral Therapy at Adult Infectious Disease Centre at the University Teaching Hospital
… to CVD comorbidity were utilised. Results: The incidence of CVD among PIs was 62% versus 38% for the non-PI ART group. The risk of CVD was found to be 2.3 times higher in the PIs ART group than non-PI ART group. Associated factors include; age, CD4 cell count, type of ART, years since HIV …
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Contemporary Outcomes of Distal Lower Extremity Bypass for Chronic Limb Threatening Ischemia and a Model Based Comparison with Non-Surgical Therapies
… randomized clinical trial of cell therapy. Incidence of major amputation after distal bypass was estimated for the VQI cohort by conduit type using non-parametric survival analysis with death as a competing risk. A cox proportional hazards model was then fit to the pooled data in a stepwise …
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Future Preventive Gene Therapy of Polygenic Diseases from a Population Genetics Perspective
… late-onset diseases that display both high cumulative incidence at an older age and high initial familial heritability will show diminishing discovery power when they use progressively older age-matched cohorts. Such studies may benefit from using the youngest possible case cohorts, …
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