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Showing 1 to 3 of 3 for “"crotonylation"”.

  1. Insights into the molecular mechanisms of function and regulation of histone crotonylation

    … their functional significance. Histone crotonylation is a well-conserved PTM, structurally similar, but functionally distinct to the well-studied acetylation. Its levels are sensitive to changes in the availability of the physiologically-relevant microbiota-derived short-chain fatty …

    cambridge Repository record for Insights into the molecular mechanisms of function and regulation of histone crotonylation (opens in a new tab)

  2. Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation

    … Lysine propionylation, butyrylation, and crotonylation were all discovered by proteomics-based approaches as I started in the Allis Lab. With reports suggesting that lysine crotonylation (Kcr) was the most functionally distinct from Kac I embarked to purify and identify the writers, …

    rockefeller Repository record for Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation (opens in a new tab)

  3. Microbiota regulate short chain fatty acids and influence histone acylations in intestinal epithelial cells.

    … include histone acetylation, butyrylation and crotonylation. Histone post-translational modifications are thought to be involved in the regulation of gene expression as they can specifically recruit transcription factors and chromatin remodellers. Histone acylations are abundant in the …

    cambridge Repository record for Microbiota regulate short chain fatty acids and influence histone acylations in intestinal epithelial cells. (opens in a new tab)