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Showing 1 to 1 of 1 for “"crossover maturation efficiency"”.
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ATM plays multiple roles in crossover regulation during mouse spermatogenesis
… of homologous chromosomes must have at least one crossover recombination event, or they risk randomly segregating, leading to aneuploidy—a major cause of infertility, miscarriage, and birth defects. In humans, approximately 1 in 20 sperm and 1 in 4 oocytes are aneuploid many from errors in …