Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 189 for “"crosslink"”.
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Factors influencing crosslink formation in muscle tissue
… this study were to determine the effect of the crosslink breaker ALT-711 on the concentration of soluble collagen, as well as its effectiveness on meat tenderness.;Final body weights were not affected by treatments. Muscle tenderness was higher (p < 0.05) for TB, SS, BF, ST, and LT (p < 0.10) …
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Precision Pointing for the CubeSat Laser Infrared CrosslinK (CLICK) Mission
… links. NASA’s CubeSat Laser Infrared CrosslinK (CLICK) Mission aims to be the first to demonstrate optical space-to-space communication on a CubeSat scale using Commercial Off the Shelf (COTS) components that include a micro electromechanical system (MEMS) fine steering mirror for …
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Studien zur Quervernetzung von Milchproteinen und zur Bildung individueller Crosslink-Aminosäuren
… um in der Folge den Anteil von unbekannten Crosslinks für die analysierten Lebensmittel bestimmen zu können. Die Identifizierung dieser vorhandenen, jedoch strukturell unbekannten Crosslinks ist ein weiteres Ziel der vorliegenden Untersuchungen. Hierbei richtet sich das Interesse vor allem …
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Correlation of permeability, hydration, and crosslink density in polyelectrolyte hydrogel membranes
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1988.
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EXPERIMENTAL STUDIES OF THE MECHANICAL BEHAVIOR OF A PVA DUAL-CROSSLINK HYDROGEL
… understand the mechanical behavior of a PVA dual-crosslink hydrogel using both experimental and theoretical tools, with more focus on the experimental aspects. This PVA hydrogel is crosslinked by both chemical (permanent) and physical (transient) crosslinks. The chemical crosslinks remain attached …
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DNA crosslink repair safeguards genomic stability during pre-meiotic germ cell development
… endonuclease XPF-ERCC1 in Fanconi-mediated DNA crosslink repair during germ cell development in utero. Inactivation of Fanconi-mediated DNA repair results in an almost complete loss of gamete production in mice. This repair pathway is critical for the normal development of primordial germ cells …
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Decentralized on-board planning and scheduling for crosslink-enabled Earth-observing constellations
… a future where high data-rate payloads and crosslinks can provide improved geospatial and temporal coverage, while at a fraction of the cost. Planning and scheduling for efficient bulk data routing with discrete crosslink windows in a dynamic network is a difficult combinatorial optimization …
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Commanding, Telemetry, and Software Strategy for CubeSat Laser Infrared CrosslinK (CLICK) Mission
… of the NASA-sponsored Cubesat Laser Infrared CrosslinK (CLICK) B/C mission [1] [2]. This twin-cubesat mission will demonstrate peer-to-peer laser-communication capabilities novel at this small terminal scale. Optical laser communication terminals can have lower Size, Weight, and Power (SWaP) …
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Nucleotide Excision Repair, Crosslink Repair and Transcriptional Function of Xpa In Human Cells
… of mammalian cells to DNA interstrand crosslinks (ICL)-generating agents. I found that XPA is retained on damaged DNA following exposure to UVA-activated psoralen, and investigated repair of a triplex forming oligonucleotide (TFO)-directed psoralen ICL. A TFO-directed psoralen DNA ICL …
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Effects of degradation rate and crosslink density of artificial skin on wound contraction
Thesis: M.S., Massachusetts Institute of Technology, Department of Mechanical Engineering, 1986
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Fundamental Importance of Fillers, Cure Condition, and Crosslink Density on Model Epoxy Properties
… shrinkage. The influence of the model epoxy crosslink density was examined by varying the content of 1,4-butanediol in the model system. Addition of 1,4-butanediol led to a decrease in the modulus and glass transition temperature, which resulted in a reduction in residual stress and …
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Fanconi Anaemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mammalian development
… I show that Fanconi Anaemia DNA inter-strand crosslink (FA ICL) repair factors act in concert to restrict LINE-1 retrotransposition. Moreover, by purifying the recombinant FA ICL repair incision complex (SLX4-XPF-ERCC1), I show that it can cleave intermediates of retrotransposition, aborting …
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Separate Roles of FAN1 and Fanconi Anemia Proteins in DNA Interstrand Crosslink Repair and Human Disease
<p>DNA interstrand crosslink (ICL) repair is vital for cellular proliferation and survival. Defects in the repair of DNA crosslinks have been associated with congenital abnormalities, bone marrow and kidney failure, liver dysfunction, and cancer. DNA nucleases play a significant role during the …
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Effect of Crosslink Density on the Tearing of Gum Natural Rubber Cured with Dicumyl Peroxide (DCP)
… peroxide (DCP) was studied. The effect of crosslink density on tensile strength, tear strength, strain, 100% modulus, and the critical cut size was determined. Dumbbell specimens cured with different level of DCP with (normal tensile test) and without (tear test) edge cuts, were strained …
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Synthetic Routes to Therapeutic Agents Via Masked Functionalities: From Orthogonal Peptide Crosslink to Photothermal Cancer Prodrug
… are a family of compounds distinguished by their crosslinking ô-histidinoalanine (ô-HAL) residue. Part one of this dissertation details the synthesis of an orthogonally protected ô-HAL building block that will be incorporated into a total synthesis of theonellamide C. Selective deprotection of …
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Characterisation of the reaction of 1,4-phenylenebismaleimide with Ca²⁺-ATPase and elucidation of the intramolecular crosslink site
… to allow muscle relaxation. The sulfhydryl crosslinker, 1,4- phenylenebismaleimide, reacts with Ca²⁺-ATPase (110 kD) to form a species with an apparent molecular weight of 125 kD, as well as dimers and high order oligomers, on SDS-P AGE. During the course of this study we have optimised and …
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Effects of type-I collagen fractional composition and pyridinium crosslink content on cortical bone strength in the human femur
… Changes in the reducible and non-reducible crosslink content, or changes in the ratio of crosslinks to total collagen may also occur. The present study investigated (1) type-I collagen content in cortical bone from the human femur, (2) the mature, non-reducible pyridinium crosslink content …
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Development of The Ark Assay For Quantitating Dna- Protein Crosslink Accumulation and Fanconi Anemia Pathway Involvement In The Repair Process
<p>DNA-protein crosslinks (DPCs) are a common DNA lesion naturally arising in cells, wherein protein becomes covalently and irreversibly bound to the DNA. Given their excessive size, these adducts present a significant challenge to replication and transcription, thus requiring timely and efficient …
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GNSS-based relative navigation for LEO nanosatellite laser communications
… the first Low-Earth orbit (LEO) nanosatellite crosslink. The need for precise and accurate pointing with laser instruments motivates a formalized, systematic approach to fulfilling this need called Pointing, Acquisition, and Tracking (PAT). The focus of this work is the initial Global …
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