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Identifying cross-species regimens for the treatment of rapid-growing and slow-growing nontuberculous Mycobacterium pulmonary infections

Whittel, Nicholas, author, Slayden, Richard, advisor, Crick, Dean, committee member, Abdo, Zaid, committee member, Wilusz, Jeffrey, committee member, Geiss, Brian, committee member, Tjalkens, Ron, committee memberColorado State University. Libraries2026

… between Mycobacterium tuberculosis (TB) and NTM species, TB standard-of-care (SoC) drugs were evaluated for repurposing to develop regimens with activity across diverse NTM pathogens. Comparative genomics using the Distilled Refined Annotation of Metabolism (DRAM) tool demonstrated that …

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