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Showing 1 to 20 of 115 for “"cross-reactivity"”.

  1. Cross-reactivity among alphaviruses provides insight into viral emergence and novel defense strategies

    Webb, Emily MorganVirginia Tech2022

    … anti-CHIKV neutralizing antibodies can provide cross-protective immunity against MAYV disease. Alongside these studies, we have characterized the potency of a camelid-derived single-domain antibody (sdAb) that neutralizes a breadth of alphaviruses, including CHIKV and MAYV. With these data, we …

    vt Repository record

  2. CROSS-REACTIVITY BETWEEN MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN AND ROUS SARCOMA VIRUS-INDUCED TUMOR ANTIGEN IN CHICKENS

    HEINZELMANN, ERIC WARREN

    <p>Cross-reactivity between major histocompatibility complex (MHC) antigen and Rous sarcoma virus (RSV)-induced tumor associated antigen (TAA) in chickens was investigated. The B erythrocyte allcantigen locus was the genetic marker for the MHC. B2B2 and B5B5 chickens from crosses of highly inbred …

    unh-thes Repository record

  3. Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping

    Njuguna, Nicholas MDepartment of Chemistry2014

    Natural products have been exploited by humans as the most consistently reliable source of medicines for hundreds of years. Owing to the great diversity in chemical scaffolds they encompass, these compounds provide an almost limitless starting point for the discovery and development of novel …

    cape-town Repository record

  4. Molecular characterisation of parvalbumin and analysis of cross-reactivity in five fish species using sera from fish-allergic consumers and occupationally exposed workers

    Beale, JanineDepartment of Human Biology2008

    … Importantly, this allergen displays lgE cross-reactivity thus allergic sufferers can exhibit clinical symptoms after the ingestion of non-sesitising fish species. In an occupational setting, fish products have also been shown to cause allergic disease in fish-processing factory workers. …

    cape-town Repository record

  5. DNA-DNA Checkerboard Hybridization to Identify Bacteria in Human Plaque Samples

    Zimmerman, Jasan Lee

    … in the subgingival patient plaque samples. Probe cross-reactivity tests were also performed and have shown that there was very little cross-reactivity between the 15 bacterial species used. This method can be used for rapid and specific identification (compared to current anaerobic culturing …

    loma-linda Repository record

  6. Antigenic Relationship of Different Porcine Rotavirus Isolates and the Identification of a New Porcine Strain

    Welter, Mark W.Drake University1983

    … isolates as measured by the vaccine's serologic cross-reactivity in vitro. Procedures. Four virulent isolates of porcine rotavirus were adapted to tissue culture. Purified viral antigens were prepared from low passage tissue culture adapted virus fluids. Upon purification both complete and …

    drake Repository record

  7. Immunologische Kreuzreaktivität zwischen dem Myelin-Oligodendrozyten-Glykoprotein (MOG) und Butyrophilin (BTN) bei Multipler Sklerose

    Guggenmos, JohannesLudwig-Maximilians-Universität

    … and that MOG exhibits extensive immunological cross-reactivity with the bovine milk protein butyrophilin (BTN), an ubiquitous dietary antigen. In a subset of MS patients this cross-reactive antibody response is significantly enhanced and are selectively sequestered in the central nervous system …

    lmu-germany Repository record

  8. The role of Human Endogenous Retrovirus K10 (HERV-K10) in the pathogenesis of rheumatoid arthritis via molecular mimicry

    Trela, MalgorzataUniversity of Wolverhampton2019

    … could provide a key epitope important for auto-reactivity in RA. Analysis of how HERV-K10 may evoke immune responses in RA was broadened by investigation of serological cross-reactivity of novel anti-K10 polyclonal antibody (PAbMAG) with IgG1 Fc. We showed that PAbMAG cross-reacted with linear …

    wlv Repository record

  9. Mounting Sex Pheromone: A Novel Pheromone Responsible for Mate Recognition in the Ixodidae

    Hamilton, JGC2019

    … assisting the male in mate recognition.</p> <p>Cross reactivity was demonstrated particularly within genera and was also demonstrated between genera. The cross reactivity may be related to the presence of sterol esters on all the species of female ticks examined.</p>

    odu Repository record

  10. IgE-reactivity and proinflammatory cytokine -inducibility of various recombinant house dust mite allergens including novel rDer f 4

    김, 충열2016

    … f 1 (89.2%) and rDer f 2 (96.4%) showed high reactivity to IgE in Korean HDM-sensitized patient’s sera. rDer f 3 (61.9%), nDer f 4 (75.8%), rDer f 5 (64.9%), rDer f 7 (43.8%), rDer f 21 (66.0%), and rDer f 23 (43.3%) exhibited moderate IgE reactivity them. IgE reactivity of rDer f 10 (24.7%), …

    ajou Repository record

  11. INFECTION- AND VACCINE-INDUCED IMMUNE RESPONSES TO SARS-COV-2 AND OTHER HUMAN CORONAVIRUSES

    Aguinam, ErnestUniversity of Cambridge2024

    … emerged in December 2019 and spread across the world causing the COVID-19 pandemic. Unprecedented efforts by scientists across the world saw the development and approval of different mRNA and adenovirus-vectored vaccines targeting the spike protein of the virus to protect against …

    cambridge Repository record

  12. Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa: implications for HIV vaccine design

    Zembe, LyciasDivision of Virology2012

    … priority. The genetic diversity of the virus across the globe is a major impediment to developing an effective vaccine. Whether a universal vaccine is possible still remain elusive. Therefore, there is need to fully characterise clusters of commonly targeted regions across the different HIV-1 …

    cape-town Repository record

  13. Avaliação de antígenos recombinantes no imunodiagnóstico da infecção por Strongyloides stercoralis em área endêmica para enteroparasitoses

    Sampaio, Maria Rita de MeloUniversidade Federal da Bagia2024

    … by challenges related to antigen production and cross-reactivity. To improve diagnostic accuracy, recombinant antigens (rSs-NIE-1 and rSs-IR) have recently been employed in the immunodiagnosis of S. stercoralis infection. Aim: This study aimed to evaluate the sensitivity and specificity of …

    brazil-ufba Repository record

  14. Characterization of viral- and fungal-reactive CD4+ T cells in healthy and diseased

    Rios Martini, GabrielaChristian-Albrechts-Universität zu Kiel

    … T cell repertoires, antigen specificity and cross reactivity. The first study demonstrates that the quality of immune responses to SARS-CoV-2-vaccination is strongly influenced by the pre-existing CD4+ T cell repertoire. Robust immunity is associated with the expansion of high-avidity …

    cau-kiel Repository record

  15. QSAR study of immunotoxicity in antibiotics.

    Bartlett, ALiverpool John Moores University1995

    … A highly sensitive assay for the quantitation of cross-reactivity between B-lactams and serum anti-benzylpenicillin antibodies has been developed and used to determine the cross-reactivity potential of 31 ~-lactams and to develop 18 QSAR models. All of the QSARs developed suggest that the shape …

    liverpool-jm Repository record

  16. Contact allergy to textile dyes. Clinical and experimental studies on disperse azo dyes

    Malinauskiene, LauraOccupational and Environmental Dermatology Unit2012

    … Disperse Orange 1 and its metabolites and their cross-reactivity to Disperse Yellow 3, its metabolites, and PPD; and C) to determine whether eight disperse dyes, hitherto the most widely quoted as allergenic, are still used in textiles sold in various countries all over the world. Evaluation of …

    lund Repository record

  17. Visualisation and analysis of patterns in serological data using "antibody landscapes"

    Wilks, Samuel HedleyUniversity of Cambridge2017

    … against viruses far beyond the extent of cross-reactivity observed after a primary infection. Analysis of two vaccination cohorts, one receiving an antigenically advanced vaccine strain and one a more typical vaccine strain choice, revealed many of the same patterns of response as seen …

    cambridge Repository record

  18. Detection and Identification of Acinobacillus pleuropneumoniae serotype 5 by multiplex Polymerase Chain Reaction

    Lo, TerryVirginia Tech1997

    … pleuropeumoniae often have problems with cross-reactivity. To avoid the complications of antibody-antigen reactions, a PCR assay was developed to detect Actinobacillus pleuropneumoniae and identify serotype 5 strains. Primers specific to the conserved capsular export region of A. …

    vt Repository record

  19. Detection of Actinobacillus Pleuropneumoniae and Identification of Serotypes 1, 2, and 8 by Multiplex Polymerase Chain Reaction

    Schuchert, Jennifer AnnVirginia Tech2002

    … pleuropneumoniae have been problematic due to cross- reactivity between serotypes, particularly serotypes 6 and 8. To avoid these serological cross-reactions, a multiplex PCR assay was developed to detect A. pleuropneumoniae and identify serotypes 1, 2, and 8. Primers specific to the conserved …

    vt Repository record

  20. Studies of recognition and selectivity by fluorescent polymers imprinted with N1-benzylidene pyridine-2-carboxamidrazones

    Ge, YiAston University2002

    … their recognition of the original template and cross-reactivity to similar test molecules. Dramatic quenching of fluorescence approaching background levels was observed for most cases where the "empty" molecularly imprinted polymer was re-exposed to its template. Molecules too large to enter the …

    aston Repository record

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