Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"cross-bridges"”.
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Structure of Cross-Bridges in Vertebrate Skeletal Muscle Activated by Photolysis of Caged Ca2+
… the structural and mechanical details of the cross-bridge cycle on the millisecond time scale. Using electron microscopy, I investigated the structure of cross-bridges in fibers activated by photolysis of caged ca2+ and then ultrarapidly frozen and freeze substituted with tannic acid and OsO4. …
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The identification and characterization of unique FemX homologue in B. burgdorferi, and insights into the peptidoglycan biosynthesis pathway
… peptide stems, interlinked by amino acid cross-bridges. PG is an essential component for survival of the bacterial cell, protecting it from the osmotic stress and environmental threats, as well as defining the shape of the bacterium and aiding in the motility. One unique feature of the B. …
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A Proposed Mechanism for Enhanced Titin-Based Force during Ca2+-activation
… investigated using chemical inhibition of cross-bridges which shows that titin force enhancement is initiated with the development of contractile force. The next set of studies increase support for an interdependence of titin force enhancement and contractile force, showing that titin force …
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The role of the apparent rate constant of cross-bridge transition from the strong binding state (G app ) in skeletal muscle force production
Force regulation at the level of the actin-myosin cross-bridge (XB) can be described by a 2 state model in which the XB's cycle between a strongly bound (SB), force generating state and a weakly bound (WB), non-force generating state. This cycle can be characterized by the apparent rate constants …
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Tensile properties of ovine skeletal muscle fibres: Thermal denaturation and selective removal of titin.
… denatured fibres, independent of the number of cross-bridges that had formed prior to cooking. As the I-band increased in length in the raw state, the more compliant the fibres became after cooking. This thesis provides information on, and a better understanding of, the structural and mechanical …
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Extracellular Matrix Degradation and Mechanical Integrity of Degenerated Human Annulus Fibrosus from Surgical Specimens
… which binds adjacent collagen lamellae via cross-bridges, is a key determinant of AF mechanical integrity, but whether its weakening is driven by aging, pathology, or both and whether this weakening is linked to proteinase-mediated extracellular matrix (ECM) degradation, has not been …
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The architectural complexity of the human PDC core assembly
… the possible existence of a network of E3 ‘cross-bridges’ linking pairs of E3BP molecules across the surface of the E2 core assembly. Low resolution solution structures obtained for rE2/E3BP, bE2/E3BP and tLi19/tLi30 by small angle x-ray scattering (SAXS) and SANS revealed the presence of …