Global ETD Search
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Showing 1 to 3 of 3 for “"coxibs"”.
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Development of Novel, Brain Permeable, mPGES-1 Inhibitors for Inflammatory Conditions
… bleeding. COX-2 selective inhibitors (COXIBs) were then developed to combat the gastrointestinal bleeding induced by nonselective NSAIDs by specifically inhibiting the COX enzyme most infamous for its role in inflammation. Yet, soon after entering the market it became apparent that …
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Metabolomic Insights into the Pharmacological and Genetic Inhibition of Cyclooxygenase-2
… The cyclooxygenase (COX)-2 inhibitors, or “coxibs,” are excellent anti-inflammatory agents, but their reputation has been tarnished by the adverse cardiovascular (CV) events, including heart failure (HF), with which they are associated. Whilst the risk of HF represents the greatest adverse …
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Cоx-2 inhibitоrѕ in Оeѕоphаgeаl Cаncer
… NSAIDs: 0.29, (0.19-0.41) and COX-2 Blockers (Coxibs) 0.35, (0.16-0.78). LOS relaxing drugs were consumed more frequently in cases of OC as compared to the controls. Other NSAIDs include propionic acid, acetic acid, enolic acid and fenamic acid derivatives. The OR for LOS relaxing drugs are: …