Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"counterregulation"”.
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Role Of Hyperglycemia, Hypoglycemia, and Glucose Transporter 4 on Brain Glucose Sensing, Counterregulation, and Neuronal Viability
As glucose is the main fuel source for the brain and a major nutrient for peripheral tissues, the brain must sense and respond to changes in blood glucose in order to sustain its own nutritional requirements and maintain whole body energy homeostasis. Disruption of brain glucose sensing results in …
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Effects Of Sustained Release Somatostatin Type 2 Antagonism On Glucagon Counterregulation And Glycemia In Type 2 Diabetic Rate Model
This thesis examined whether a novel somatostatin receptor 2 antagonist (SSTR2a), ZT-01, could enhance endogenous glucagon secretion and protect against hypoglycemia in a rat model of type 2 diabetes (T2D). Male Sprague Dawley rats were placed on a high-fat diet and injected with streptozotocin to …
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A self-regulation analysis of dietary restraint
… Finally, the concepts of dietary restraint and counterregulation are critically evaluated in light of the present results.
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Glucosensing, Hypoglycemia, and the Brain
… In addition, the brain regulates hypoglycemic counterregulation. Hypoglycemia is a major limitation to the treatment of diabetes. Severe hypoglycemia can lead to brain damage, cognitive dysfunction, and death. Understanding how to prevent the complications of severe hypoglycemia is critical to …
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Brain Insulin Action Regulates Hypothalamic Glucose Sensing and the Counterregulatory Response to Hypoglycemia
… and respond to hypoglycemia by analyzing glucose counterregulation and neuronal activation in response to hypoglycemia. Further, to clarify a mechanism of CNS insulin action, this study assessed whether insulin regulates key glucose sensors and/or CNS glucose uptake by examining the expression …
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Hypoglycemia-induced changes in glucose metabolism in the hypothalamus
… in the development of impaired glucose counterregulation.