Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"cortistatin"”.
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Part I. Total Synthesis and Structural Revision of (±)-Tricholomalides A and B. Part II. Synthetic Studies towards (+)-Cortistatin A
… part describes the synthetic studies towards (+)-cortistatin A, especially the A ring functionalization. The C3 nitrogen was introduced by azide displacement, and C2 hydroxyl was built up by Luche reduction. The challenging C1 functionalization was achieved with bromine-induced methoxymethyl …
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First survey and functional annotation of prohormone and convertase genes in the pig
… databases. These genes are Intermedin (ADM2), Cortistatin (CORT), Insulin-like 5 (INSL5), Orexigenic neuropeptide QRFP (OX26), Prokineticin 2 (PROK2), Prolactin-releasing peptide (PRRP), neuropeptide S (NPS), Parathyroid hormone 2 (TIP39), Urocortin (UCN1), Urocortin 2 (UCN2), Urocortin 3 …
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MOLECULAR MECHANISMS UNDERLYING CLINICAL BEHAVIOR OF NEUROENDOCRINE TUMORS: STUDY OF NEW POSSIBLE BIOMARKERS PREDICTABLE OF PHARMACOLOGICAL RESISTANCE AND TARGETS
… pathways in PitNETs and on somatostatin/cortistatin system in novel PanNENs cell models. Briefly, β-arrestin 2 has been highlighted as novel potential biomarker of pharmacological responsiveness to DAs, and that combined therapy with DAs avoids everolimus escape feed-back in PitNETs. The …
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An Investigation of Gold(I) Catalyzed Cycloaddition Reactions
Unit I, Two successful 13- and 15-membered macrocycles containing furan and α-chloroketone functional groups were synthesized. Macrocycles were subjected to solvent mixture (Et<sub>3</sub>N, CF<sub>3</sub>CH<sub>2</sub>OH, and Et<sub>2</sub>O), and an oxyallyl cation was presumably formed, which …