Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 25 for “"cortical layers"”.
-
fMRI of cortical layers
Contains fulltext : 91455.pdf (Publisher’s version ) (Open Access)
-
Population Coding In Laminar Cortical Circuits
… of neuronal networks is organized according to cortical layers raises the possibility that sensory information could be processed differently in distinct layers. The goal of my thesis research is to understand how laminar circuits encode information in their population activity, how the …
-
Target-specific contrast agents for magnetic resonance microscopy
… images between the deeper, more myelinated cortical layers (IV-VI) and adjacent, superficial layers (I-III) at both field strengths. Specifically, CNR for LFB-treated samples increased by 229± 13 per cent at 4.7T and 269± 25 per cent at 14T when compared to controls. Also, additional …
-
Interlaminar Interactions in the Cat Visual Cortex (Laminae, Columns)
… is the projection of cells in supragranular layers to cells in the infragranular layers. By recording from cells in the infragranular layers during synaptic inactivation of layers 1-3, I have examined the possibility that this projection may confer certain receptive field properties upon …
-
Role of Laminin gamma 1 in Cortical Development
… disrupted in the nervous system. These mice show cortical developmental abnormalities including undulations in the embryonic cortical plate and resultant adult cortical layers and abnormal positioning of pyramidal neurons and interneurons. We have investigated the mechanisms underlying these …
-
AN ANATOMICAL AND IMMUNOCYTOCHEMICAL STUDY OF THE PRIMATE TEMPORAL AND FRONTAL CORTEX
… with specific varieties typical of individual cortical layers. The ultrastructure of the adult and infant cortex was further investigated in well-fixed biopsy specimens. Neuronal profiles were classified by correlating their light microscopic features in semithin sections with their …
-
Cholinergic Control of Cortical Circuit Activity
… role in the moment-to-moment control of ongoing cortical state transitions that occur during periods of wakefulness. Yet, the underlying circuit mechanisms of synaptic cholinergic function in the neocortex remain unclear. Moreover, acetylcholine continues to be widely viewed as a slow and diffuse …
-
Neural computation of depth from binocular disparity
… humans, we revealed systematic and reproducible cortical organization for stereoscopic depth in dorsal visual areas V3A and V3B/KO. Within these regions, depth selectivity was inversely related to depth magnitude — a key characteristic of stereoscopic perception. Finally, we report evidence for a …
-
The ontogeny and functional distribution of novel, neurochemically-defined columns in mammalian visual cortex
… was highest within superficial and deep cortical layers around postnatal day (PD) 30, while 5-HTic and 5-HT2 receptors exhibited peak levels in middle cortical layers at PD50 and PD120, respectively. Between PD30 and PD90, 5-HTic & 5-HT2 receptors were expressed at high levels within the …
-
Dividing the Preplate: Characterization of Neuronal Subpopulations in the Early Murine Cerebral Cortex
… which is comprised of the earliest generated cortical neurons. Preplate neurons are a heterogenous population of future Cajal-Retzius neurons and future subplate neurons, which are derived from multiple sources of progenitors. During the formation of the cortical layers, the preplate is split …
-
Morphological alterations in frontotemporal dementia:
… and the characteristic frontotemporal pattern of cortical degeneration. The von Economo neurons (VENs), are a particular type of neurons that are proposed to constitute this link. We confirm results from others, showing that these neurons are selectively degenerated in FTD. In addition we show …
-
Carbachol- and ACPD-Induced Phosphoinositide Responses in the Developing Rat Neocortex
… study localized PI responses to individual cortical layers in slices of developing rat somatosensory cortex. The acetylcholine agonist carbachol and the glutamate agonist trans-1-amino-1,3-cyclopentanedicarboxylic acid (ACPD) were used to stimulate PI turnover. The PI responses were compared …
-
Cellular and Circuit Level Responses to Neural Stem Cell Transplantation in the Rodent Cortex
… elicited activity that originated in deep layers, propagated vertically along cortical columns, and spread horizontally across superficial layers. Very high levels of C17.2 engraftment (>25%) interfered with parameters of cortical function, including the amplitude, spatial extent, velocity, …
-
Developmental myelination and myelin plasticity during spatial working memory task acquisition
… slowly progressing upward up from the deeper cortical layers to the surface of the brain. Furthermore, over the course of a lifespan myelin internodes lengths become more variable. This increased variability could potentially represent myelin plasticity across their lifespan. Finally, I find …
-
Cortical structure: Linking MRI and cytoarchitecture
… the problem of linking microscale post mortem cortical cytoarchitecture with millimeter-scale measures of cortical anatomy accessible through in vivo MRI. Chapter 1 introduces the problem and previous work done to address it. The following two chapters apply classical atlases of cortical …
-
Optimization-Based Methods for Reconstruction and Structural Quantification of Neurons and Glia from Microscopic Images
… and tripartite structures across different cortical layers of the mouse visual cortex in a large-scale EM dataset.
-
Spatial and temporal regulation of cerebral cortex development by the transcription factor pax6
… generation, migration and differentiation of cortical neurons. Cortical projection neurons originate from progenitors of the embryonic dorsal telencephalon. The transcription factor Pax6 is expressed in apical progenitors (APs) throughout corticogenesis in a rostro-lateralhigh to …
-
Imaging and therapy in multiple sclerosis
… reductions in the innermost (periventricular) layers and outermost (cortical) layers of patients with longstanding MS. These abnormalities are termed “outside-in” changes. The cause, extent, evolution and treatment-responsiveness of these outside-in gradients is unknown. Most patients present …
-
Electrophysiological Recording of the Brain, Visualization, Prediction, and Interconnectivity
… in the basal ganglia communicate with the cortical layers during voluntary movements. This allows investigating the inter-coupling between the sensorimotor cortex and basal ganglia and how cortico-basal ganglia coupling changes with respect to the movement. The association of coherence with …
-
The Role of Perineuronal Nets in Regulating Barrel Cortex Physiology
… dependent maturation of PNNs in different cortical layers and whether the alterations to neuronal intrinsic properties following sensory deprivation could be explained by PNN reductions. Finally, we sought to determine what aspects of intrinsic and synaptic physiology are regulated by PNNs …
Page 1 of 2