Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 358 for “"coronavirus"”.
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Cofactors in Coronavirus Entry
… fusion of virus and host cell membranes. For the coronaviruses, viral spike (S) proteins execute these cell entry functions. In my dissertation research I focused on understanding the coronavirus spike proteins as well as other cofactors required for S-mediated entry into cells.</p><p>The S …
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Charakterisierung der Helikase- und Endonukleaseaktivitäten des Humanen Coronavirus 229E und des SARS-Coronavirus
… unterschiedlicher serologischer und genetischer Coronavirus-Gruppen, parallel untersucht und ihre Eigenschaften miteinander verglichen. Die nsp13-Helikase des SARSCoronavirus wurde als bakterielles Fusionsprotein exprimiert, und die nsp13-Helikase des humanen Coronavirus 229E wurde in …
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Coronavirus Replication Inhibition by Herbal Extracts
Coronaviruses are plus-stranded RNA viruses that infect human and large variety of animals, including pig, cattle, dog, rat, rabbit, turkey, and bird. Human coronavirus has been known to cause common colds and perhaps gastroenteritis. Animal coronaviruses cause gastroenteritis, hepatitis, and a …
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In vitro inhibition of coronavirus replications
"In Vitro Inhibition of Coronavirus Replications A search for new anti-coronaviral drugs to treat coronaviral infections was motivated by an outbreak of severe acute respiratory syndrome (SARS). In order to find drugs that treat coronavirus infections, including SARS, we screened traditional …
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Conserved recombination patterns across coronavirus subgenera
… contributes to the genetic diversity found in coronaviruses and is known to be a prominent mechanism whereby they evolve. It is apparent, both from controlled experiments and in genome sequences sampled from nature, that patterns of recombination in coronaviruses are nonrandom and that this is …
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Animal models for investigating coronavirus heterotypic immunity
Endemic coronaviruses (CoVs) such as OC43 circulate seasonally and, while usually mild, represent the 6th leading cause of viral pneumonia. Additionally, multiple zoonotic spillovers of CoVs have occurred in the last 25 years to cause severe pneumonia, most recently the coronavirus disease 2019 …
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Receptor Binding Domains and Coronavirus Adaptation and Evolution
Coronaviruses are enveloped RNA viruses that cause respiratory diseases in humans and other animals. The continued circulation of human coronaviruses and the large reservoir of non-human coronaviruses that have the potential to infect humans represent a significant health concern. Similar to other …
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La cura "milagrosa" para el coronavirus en Popayán
… Popayán, a raíz de la pandemia causada por el coronavirus. Popayán dio qué hablar desde que la pandemia mandó a encerrar a todo el mundo. El alcalde de la ciudad, Juan Carlos López Castrillón, atrajo la atención de más de un medio de comunicación, primero, porque el mandatario acababa de llegar …
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“Impacto del Coronavirus en el Sector Retail Financiero”
Este informe, analiza el impacto económico de la crisis sanitaria - COVID-19 - en el mercado financiero, mostrando que el mundo esta fuertemente conectado e integrado y los impactos de la enfermedad van mucho más allá de la mortalidad, porque hemos visto en diferentes países severos bloqueos que …
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THERE’S NO CRYING IN BASEBALL (UNTIL CORONAVIRUS COMES AROUND)
<p>This study sought to investigate fan reactions to the NCAA communication around the elimination of NC State from the 2021 Baseball College World Series. NC State was eliminated due to Covid-19 protocols. A content analysis was conducted by looking at posts from various NCAA related accounts on …
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Human Antibody Response to Flaviviruses and SARS-Coronavirus-2
… (ZIKV) and severe acute respiratory syndrome coronavirus (SARS-CoV-2). The first part of this thesis focuses on encephalitis-causing tick-borne flaviviruses, specifically TBEV and POWV. Both TBEV and POWV are emerging human pathogens that cause potentially fatal disease; there are no …
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Covid-19 (Coronavirus) Disease Diagnosis Using Fuzzy Inference System
… This research study aims to diagnose the coronavirus (COVID-19) diseases symptoms using an Intelligent Systems approach. The COVID-19 epidemic is currently one of the most deadly diseases in the world. The pandemic has affected human life and global economy adversely at a large scale. It …
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Genetics and functions of the SARS coronavirus spike protein
The SARS-Coronavirus (SARS-CoV) is the etiological agent of the severe acute respiratory syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events during virus entry and virus-induced cell-to-cell fusion. Investigations, described herein, have focused on the genetic …
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Human coronavirus NL63 envelope protein-protein interactions: role in pathogenesis
Human coronaviruses (HCoVs) have garnered intense interest due to the large outbreaks caused by severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which have …
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Coronavirus Proteases as Therapeutic Targets: Development of Biosensors to Detect Inhibition of Protease Activity and Separation of the Multiple Functions of Coronavirus Papain-Like Proteases
<p>Coronaviruses are important human pathogens and have the potential to severely impact public health on an international scale. The emergence of SARS-CoV and MERS-CoV highlight the need for research to identify antivirals and vaccines against coronaviruses. To develop therapeutics against current …
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The Coronavirus Pandemic and the Mental Health Presentations of Young Children
Children under the age of four are emotionally vulnerable to global disasters such as the COVID-19 pandemic because of the lack of socialization opportunities and coping mechanisms, and susceptibility to heightened caregiver stress. Currently, the extent to which the pandemic impacted the mental …
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Antibody production with synthetic peptides against human Coronavirus-NL63 ORF3 protein
Human Coronavirus (HCoV) NL63 was detected in an infant in the Netherlands in 2004 and will hereafter be referred to as CoV-NL63. Four years later, it was classified into Group 1 coronaviruses by the International Committee for Taxonomy of Viruses (ICTV), which was modified into alphacoronavirus in …
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Coronavirus Replicase Proteins: Multifunctional Mediators of Replication and Innate Immunity Evasion
<p>Coronaviruses are positive-sense, single-stranded RNA viruses. The majority of the RNA encodes non-structural proteins (nsps) that are translated as a large polyprotein, which is cleaved by the papain-like (PLP) and picornavirus 3C-like (3CLpro) proteases. The nsps modify host membranes to …
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