Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1646 for “"copy"”.
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Transformative copy
… What if that would not be the case, if each copy of a digital file would go along with some sort of transformation? This thesis examines the implications of such a scenario on information ecologies and map out the design space for a new type of decentralized authoring applications. The …
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Copy-and-Paste
Copy-and-Paste is a self-sustaining system generating sameness in different locations. The same urban grid, the same outfit, the same house, the same car appear everywhere; copies of each other pasted all around. Copy-and-Paste is there, unquestioned, and seem-to-be arbitrary. This thesis explores …
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Copy-raising in Koine Greek
… results from the application of the rule COPY-RAISING in the derivation of a sentence. COPY-RAISING claims that any noun phrase that is a constituent of a complement clause may be duplicated or copied, the copy being then raised into the clause of which the complement clause is a …
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COVER-COPY-COMPARE: A LITERATURE REVIEW
<p>Cover-copy-compare (CCC) is an evidence-based math intervention strategy that can be used to help to build math fact accuracy and fluency. This literature review aims to examine different modifications of CCC, the effectiveness of CCC in helping students with disabilities, and identifying …
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Zero-Copy Communication for Efficient Compound Processes
… transitions, disturb caches, and repeatedly copy data, overheads that quickly become dominant in data-intensive workloads. The Compound Processes framework reduces some of these costs by allowing multiple cooperating guests to run inside a shared, trusted environment, but its current …
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Geometric Verification of Image Copy Detection Results
Many current image recognition methods are based on identifying interest points in images and considering images a match if they share similar interest points. This does not consider the locations of the interest points, so to reduce the number of false positives, geometric verification is used to …
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Clinical Interpretation of Novel Copy Number Variations
Copy Number Variations: CNVs) are a significant source of human genetic diversity and are believed to be responsible for a wide variety of phenotypic variation. Recent advances in microarray-based genomic hybridization techniques have facilitated CNV analysis as a viable diagnostic technique in the …
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Application of the Copy Exact methodology to systems implementation
… and knowledge transfer commonly referred to as Copy Exact. This method, often associated with technology transfer in semiconductor fabrication facilities, can be readily applied to implementation of large-scale information systems. By sharing the collective knowledge and resources of multiple …
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Computational Analysis of Genome-Wide DNA Copy Number Changes
DNA copy number change is an important form of structural variation in human genome. Somatic copy number alterations (CNAs) can cause over expression of oncogenes and loss of tumor suppressor genes in tumorigenesis. Recent development of SNP array technology has facilitated studies on copy number …
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Decoding Copy Number Substructure and Evolution From Single Cell Genomics
… model of TNBC evolution is the Punctuated Copy Number Evolution (PCNE), in which tumors undergo a period of elevated genomic instability, acquiring complex genomic rearrangements within a short timeframe followed by clonal stasis. However, these observations rely on limited cell numbers and …
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Computational Insights Into The Generation of Chromosomal Copy Number Changes
… alterations — such as duplications, deletions or copy-neutral loss-of-heterozygosity — are thus important forms of genetic variation for phenotyping populations of individuals as well as populations of cells. Indeed, copy number variants (CNVs) serve as hallmarks of critical changes in the …
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Simplified Low Copy Number Dna Analysis By Post Pcr Purification
… of standard 28 cycle PCR such that low copy number DNA templates (<100 pg DNA) can be analyzed. Full profiles were consistently obtained with as little as 20 pg template DNA without increased cycle number. In mock case type samples with dermal ridge fingerprints, genetic profiles were …
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Accelerated Adaptation through Stimulated Copy Number Variation in Saccharomyces cerevisiae
Accelerated Adaptation through Stimulated Copy Number Variation in Saccharomyces cerevisiae Ryan Matthew Hull Repetitive regions of the genome, such as the centromeres, telomeres and ribosomal DNA account for a large proportion of the genetic variation between individuals. Differences in the number …
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Prevalence and prevention of large-scale somatic copy number alterations
… of megabases, as occurs with sub-chromosome copy number variants (CNVs) or whole-chromosome aneuploidy, is almost always associated with embryonic lethality or severe disease. However, while large-scale genomic imbalance has adverse consequences at the organismal level, both CNVs and …
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Evolution and vulnerabilities of somatic copy number alterations in cancer
… screens to perform an unbiased analysis of all copynumber: gene dependency interactions. We identify a class of interactions called CYCLOPS interactions in which genomic loss of essential genes sensitizes cancer cells to their further suppression. We explore the properties of CYCLOPS genes and …
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Mitochondrial DNA Copy Number, Insulinemic Potential of Lifestyle, and Colorectal Cancer
… It has been increasingly recognized that mtDNA copy number (mtDNAcn) is a biomarker for mitochondrial function and cellular oxidative stress. To date, the few studies that have assessed associations between mtDNAcn and CRC outcomes have yielded inconsistent findings. Further, no epidemiologic …
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