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Showing 1 to 7 of 7 for “"copolymer micelle"”.
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Effect of Encapsulated Species on Block Copolymer Micelle Self-Assembly
Due to their amphiphilic nature, block copolymers spontaneously form assemblies known as micelles in selective solvents. Minimization of the solution free energy drives the micellization process, with contributions from the polymer chains, surrounding solvent, and any additive molecules. Through …
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DESIGN AND SYNTHESIS OF BLOCK COPOLYMERS THAT SELF ASSEMBLE INTO MICELLES WITH CONTROLLED ACID AND LIPASE CATALYZED DEGRADATION
… glycol) (PCL-b-PEG) is typical amphiphilic block copolymer that self assembles into micelles in water where the hydrolytically stable hydrophilic PEG segment forms the exterior corona and the core contains the hydrophobic degradable PCL block. Micelles from PCL-b-PEG block copolymers are among the …
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Multiscale Transport and Dynamics in Ion-Dense Organic Electrolytes and Copolymer Micelles
… molecule into the core of a spherical block copolymer micelle (to mimic, e.g., drug loading) on the hydrodynamic radius (rH) and polymer chain dynamics. In particular, I present spin-lattice relaxation (T1) results that directly measure single chain exchange rate kexch between micelles and …
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Polyoxometalates and Block Copolymers: Templated Self-Assembly for Nanomaterials Applications
… The feasibility of templating POMs with block copolymers is demonstrated in a preliminary ionic exchange reaction. Block copolymers were explored as templates in conjunction with POMs to develop bottomup approaches for magnonic crystal fabrication. A range of block copolymers were investigated …
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Design of Artificial Modular Extracellular Matrices
… a defined distance were obtained by using block copolymer micelle nanolithography, which itself is restricted to solid, inorganic, and planar surfaces such as glass slides; the gold particles are transferred to polymers by means of a thiol-gold coupling scheme. Depending on the polymer to be …
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Development and Intratumoral Distribution of Block Copolymer Micelles as Nanomedicines for the Targeted Delivery of Chemotherapy to Solid Tumors
… into nano-sized, biocompatible PEG-b-PCL block copolymer micelles (BCMs). Encapsulation of DTX in micelles via chemical conjugation or physical entrapment resulted in a dramatic increase in drug solubility and customizable drug release rate. The use of multicellular tumor spheroids (MCTS) was …
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Synthesis and catalytic testing of a proline functionalized amphiphilic block copolymer
… The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of …