Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"controlled clinical trial"”.
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DIFFERENT TECHNIQUES FOR DENTAL IMPLANTS SITE PREPARATION: A CONTROLLED CLINICAL TRIAL
… (Step drilling sequence) could modify the clinical and/or patient-centered variables We included and treated 60 subjects, for a total of 86 implants. We found no evidence of a difference in bone resorption, which increased significantly over time, between the two groups. Regarding the …
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Behavioural Activation for Depression: a systematic review and controlled clinical trial
… recommended. Promising results from randomised trials has renewed interest in behavioural therapy, which may be suitable for delivery by non-specialist therapists. Aims To deliver a phased research programme to examine the clinical and cost effectiveness of behavioural therapy for depressed …
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SURGICAL TREATMENT OF ORAL LEUKOPLAKIA: A RANDOMIZED CONTROLLED CLINICAL TRIAL COMPARING SURGERY WITH WAIT AND SEE APPROACH
… but in literature there is no randomized clinical trial that demonstrates its real effectiveness in preventing malignant transformation. Objective: To compare the incidence of oral squamous cell carcinoma (OSCC) in a group of subjects undergoing surgical treatment and a similar group under …
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Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial
bold>ABSTRACT</bold> <bold>Objective:</bold> Test the efficacy of a green tea catechin extract (GTE) to improve lipid profile in postmenopausal women. <bold>Methods:</bold> 886 women were enrolled and randomized to consume either 1200 mg of GTE (800 mg EGCG) or placebo, daily. Fasting serum samples …
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A 4-month randomized controlled clinical trial of adjuvant exenatide or pramlintide versus insulin alone in pediatric type 1 diabetes mellitus: Effect on glycemic control
… results (n=24) of a Phase III randomized clinical trial designed to compare the glycemic effects of using adjuvant Pramlintide or Exenatide versus insulin alone in pediatric T1DM. Sample size calculations estimated 21 patients per treatment arm (63 total) are needed. So far, 24 patients …
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A pragmatic controlled clinical trial investigating the efficacy of low-level laser therapy as a part of the palliative management of the hand symptoms of rheumatoid arthritis
Submitted in fulfillment of Master's in Technology: Chiropractic, Durban Institute of Technology, Durban, South Africa, 2006.
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Temporary tissue retraction before taking impression. A multi-center randomized controlled clinical trial comparing the use of retraction cord, aluminum chloride paste (Expasyl®) and combination of aluminum chloride paste and retraction cord
… the classic method. The aim of this randomized controlled clinical trial (RCT) is to evaluate the influence of three different methods for temporary tissue retraction before impression taking on the gingiva. Additionally, patients' perception of the intervention and technicians' evaluation of …
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A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck
… of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of xerostomia is …
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Evaluation of epidural morphine and incisional bupivacaine for analgesia following hemilaminectomy in the dog
A blind, placebo–controlled clinical trial was performed to evaluate the postoperative analgesic effect of topically administered, intraoperative, epidural morphine (Duramorph™) and intramuscular infiltration of the incision site with bupivacaine prior to closure of the skin in dogs undergoing …
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Análisis de dos esquemas de tratamiento con hierro oral e intravenoso en cirugía cardiaca : ensayo clínico en fase IV, randomizado, doble ciego y doble enmascarado
… centres over the years. Objective: To test the clinical effectiveness of intravenous and oral iron supplementation in correcting anemia, and its impact on blood transfusion requirements, in patients undergoing cardiopulmonary bypass (CPB) surgery. Methods: A double-blind randomized …
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An Investigation into Long-Chain Polyunsaturated Essential Fatty Acids, Event Related Potential Assessments of Brain Function and Behavioural Measures in Children and Adolescents with and without Attention Deficit Hyperactivity Disorder
… (ERP) assessments of brain function and clinical behavioural measures. ERPs were also investigated in a randomised, double-blind, placebo-controlled clinical trial of 12 weeks PUFA supplementation in ADHD. Comparison of LC-PUFA measures between two groups of ADHD showed no differences in …
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A cross-over randomised controlled trial of selective pressure impressions for lower complete dentures and laboratory investigations into impression pressure variation
… dentures, especially in the form of randomised controlled trials (Jokstad et al 2002, Harwood 2008). The literature review from Part I suggested that selective pressure impressions for complete dentures required evidence on three levels; firstly, in-vitro evidence on the numerous factors that …
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How much Detail is needed in Cost Estimation in an Economic Evaluation alongside a Clinical Trial to Optimise Evidence for Decisions?
… resource use data alongside a randomised controlled clinical trial is particularly so due to the multidimensional nature of costs: different costs are incurred by different agencies with varying methods and systems to account for these. Trialists are faced with decisions over how to …
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Clinical Trial of Cognitive-Behavioral Therapy to Reduce Antiretroviral Side Effects in HIV Patients
… morbidity. Adherence to regimens is vital, yet clinical observations and research have suggested that side effects are a significant reason for non-adherence. This randomized, controlled clinical trial was a pilot study sought to determine if a brief exposure cognitive-behavioral therapy (CBT) …
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Effects of xanthine oxidase inhibitors in pulmonary hypertension associated with chronic lung disease
… disease (PH-CLD).In a double-blind, randomised controlled clinical trial, 72 patients with PH-CLD (93% diagnosed with chronic obstructive pulmonary disease and 17% with interstitial lung disease) were randomised to receive either allopurinol 300 mg twice daily or placebo for twelve months. The …
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The effect of spironolactone on exercise capacity in functionally impaired older people without heart failure
… heart failure. In a double-blind, randomised controlled clinical trial 120 participants, aged >65 years with functional impairment were randomized to receive 25mg spironolactone or placebo for 20 weeks. The primary outcome was the change in six-minute walking distance over 20 weeks. Secondary …
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Examination of self-determination theory constructs as mediators of the effect of motivational interviewing on tobacco cessation outcomes
… effects in a recently completed randomized controlled clinical trial comparing motivational interviewing to health education on smoking quit attempts (KC Quest). Results of the parent trial unexpectedly revealed that motivational interviewing was not more effective than health education for …
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Diabetes in children: impact of an innovative pharmaceutical care programme and links with concurrent illnesses
… main body of work was a randomised controlled trial carried out at Hamad General Hospital (HGH), Qatar. This study included 212 children ≥ 18 years of age with T1DM (Chapter 2). Those randomised to a pharmacist-managed clinic received education from a pharmacist on their condition, …
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Allopurinol as a possible oxygen sparing agent during exercise in peripheral arterial disease
… with PAD.<br/><br/>In a double-blind, randomised controlled clinical trial 50 participants with PAD were randomised to receive either allopurinol 300mg twice daily or placebo for six months. The primary outcome was change in exercise capacity on treadmill testing at six months. Secondary outcomes …
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