Global ETD Search
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Showing 1 to 3 of 3 for “"controllable release"”.
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Trigger-responsive nanomedicines through controlled chemistry
… The nanoparticles were shown to have controlled release profile in response to cancer-specific trigger. A series of dimeric CPT derivatives were designed that are responsive to various in vivo applicable triggers to study the formulation mechanism. The prodrug library suggested that the dimeric …
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Single-Payload Bioconjugation to Native Antibodies And A General Method for the Self-Immolative Release of Amide-Containing Molecules
… of the antibody and the payload. The controlled release of drug molecules is of interest across various chemical fields. It allows for the masking of a molecule's properties and precise deployment upon a single controllable release event. Although numerous methodologies have been developed for …
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Self-assembled Peptide Hydrogels for Therapeutic H2S Delivery
… After the addition of cysteine, H2S was released from the APAs with half-lives ranging from 13 min to 31 min. The electron-donating groups slowed down the H2S release rate, while the electron-withdrawing groups accelerated the release rate. Therefore, the release rates of H2S were …