Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 41 for “"control arm"”.
-
Lung carcinogenesis modeling: Resampling and simulation approach to model fitting, validation, and prediction
… the combination of risk factor data from a case-control study, and tabled incidence/mortality rate data. A simulation study of the method shows that it is accurate in estimating the parameters of the TSCE model. The method is then applied to fit a TSCE model based on smoking history. The fitted …
-
Anti-sway control of a construction crane modeled as a two-dimensional pendulum
… in the hands of the operator. The problem of controlling sway of the load due to crane motion, or wind effects must be solved dynamically by the operator to increase productivity and maintain safety. At the hands of inexperienced operators safety is sometimes sacrificed in order to expedite …
-
A 4-month randomized controlled clinical trial of adjuvant exenatide or pramlintide versus insulin alone in pediatric type 1 diabetes mellitus: Effect on glycemic control
… or Pramlintide versus insulin alone on glycemic control, as measured by glycated hemoglobin (HbA1C) and 1,5-Anhydroglucitol (1,5-AG), or GlycoMark, in pediatric Type 1 Diabetes Mellitus (T1DM). We present here the preliminary results (n=24) of a Phase III randomized clinical trial designed to …
-
Recent Advances on Statistical Network Analysis and Multi-task Learning for Complex Data
… I develop an ERGM to generate networks while controlling for bicliques, which are the characterizing graph substructures for generating CK. Second, according to FDA guidance, prognostic variables—baseline covariates associated with clinical trial study outcomes—must be pre-specified at the …
-
Improving Contraceptive Method Choice and Use with a Computer-Based Contraceptive Assessment Module
… to improve contraceptive choice and use. A three-arm randomized controlled trial of a bilingual (Spanish/English) contraceptive assessment module using audio-computer-assisted self-interviewing technology and touchscreen computers was conducted from March 2008 - January 2011 among family planning …
-
Effects of Combined Bevacizumab and Paclitaxel On Tumor Interstitial Fluid Pressure In A Preclinical Breast Cancer Model
… and bevacizumab produced greater tumor control than either agent given alone and this combination reduced the IFP, producing an increment of 75% of apoptosis compared with the control arm. In addition, the intra-tumor paclitaxel quantification by liquid chromatography/Mass Spectrometry …
-
A randomised controlled trial of a diet and physical activity intervention in prostate cancer patients and related studies.
… the rationale and methodology of a Randomised Controlled Trial (RCT) to test the efficacy of a 6 month combined dietary and walking intervention on alleviating the Health-Related QoL (HRQoL) issues associated with ADT treatment. Ninety-four men were recruited and randomised to the intervention …
-
The effectiveness of using patient-reported outcome measures as quality improvement tools
… of the primary research. A cluster randomised controlled trial (PROFILE) examined the impact of providing peer benchmarked PROMs feedback to consultant orthopaedic surgeons on improving outcomes for hip replacement surgery. Qualitative interviews with surgeons in the intervention arm of the …
-
Improving Lung Cancer Risk Prediction: Integration of Novel Predictors and Modelling Using Machine Learning Random Forest versus the Validated PLCOm2012 Logistic Regression Model
… Ovarian (PLCO) Cancer Screening Trial control arm (n=43,217) and validated using the PLCO intervention arm (n=42,493). Logistic regression (LR), and random forest (RF) methodology were analyzed using R software. The models were evaluated based on their ability to predict 6-year LC risk …
-
Using a birth ball in the latent phase of labour to reduce pain perception; a randomised controlled trial.
… their pain perception. As a pragmatic randomised controlled single centre trial, 294 low risk women were randomly allocated to two groups. At 36 weeks’ gestation the Intervention Arm accessed the infomercial online and completed a modified Childbirth Self- Efficacy Inventory before and after …
-
Algorithms and systems for home telemonitoring in biomedical applications
… lack of standardization and continuous medical control cause the patients neglecting this therapeutic procedures. Telemonitoring the rehabilitation sessions would allow the physician to closely follow the patients' progresses and compliance to the prescribed adapted exercises. This application …
-
An Approach to Using Finite Element Models to Predict Suspension Member Loads in a Formula SAE Vehicle
… This involves welding the members of each control arm together at the outboard point as well as creating a simplified version of the pull rod mounting bracket on the upper control arm. The pull rod is the member that connects the ride spring, damper, and anti-roll bar to the wheel assembly …
-
Team-based electronic communication in the care of patients with complex conditions
… The second study was a cluster randomized controlled feasibility trial evaluating the feasibility of implementation and preliminary effectiveness of a web-based tool for asynchronous, patient-provider team-based communication on continuity of care relative to usual care. Finally, a …
-
The Rapid Detection of MRSA
<p>The control of meticillin-resistant<em> Staphylococcus aureus </em>(MRSA) is a global healthcare priority. Screening patients for MRSA carriage occupies a central position in this control. Conventional culture methods for MRSA screening take 2-3 days to produce a positive result. Polymerase …
-
Understanding effective communication in dental primary care: the dentally anxious patient, an example of special care dentistry
… randomised to start either with the experimental arm, where dentally anxious patients (MDAS score = 19 or 5 in any one question) complete and handover MDAS to the dentist, or the control arm where no handover occurred. Within the observational study, all participants had their dental treatment …
-
Benzodiazépines et thérapie cognitive-comportementale transdiagnostique de groupe pour les troubles anxieux : une étude mixte
… with an anxiety disorder to already use a pharmacological treatment, including benzodiazepines. However, the effect of combining benzodiazepines with CBT is unclear. Objective: This study has two main objectives: (a) to explore the influence of pretreatment benzodiazepines use on the …
-
Does Blood Flow Restriction Applied Post High-Load Exercise Augment Skeletal Muscle Growth Following Eight Weeks of Training?
… individuals performed 24 training sessions. The control arm performed one set of elbow flexion (70% 1RM) exercise to volitional fatigue, while the experimental arm performed the same protocol immediately folloby 3 min of blood flow restriction (70% arterial occlusion). Both conditions completed …
-
Neurophysiological effects of arm weight support: Implications for stroke rehabilitation
Arm weight support may be used as an adjuvant to increase training dosage and improve movement quality during upper limb stroke rehabilitation. However, the underlying neurophysiological effects of weight support are not well understood. The aim of this thesis was to investigate the …
-
Novel methods for early phase clinical trials
… singleagent data, including toxicity and pharmacokinetic exposure information, is available. This information is used to define escalation rules that combine the outputs of independent dose-toxicity and dose-exposure models which are fitted to emerging trial data. This solution is practical …
Page 1 of 3