Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"contralateral breast cancer"”.
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Predictors of Contralateral Breast Cancer In Brca Negative Women
<p>Breast cancer is the most common cancer diagnosis and second leading cause of death in women. Risk factors associated with breast cancer include: increased age, alcohol consumption, cigarette smoking, white race, physical inactivity, benign breast conditions, reproductive and hormonal factors, …
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Molecular and genetic characterisation of contralateral breast cancer (CBC): opportunities for personalised surgery
… investigate the relationship between primary and contralateral breast cancers (CBCs). Additionally, given the known risk factors for CBC development of young age at primary diagnosis and significant family history, the genetic predisposition of the CBC cohort was assessed.<br/><br/>Firstly, the …
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Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer.
One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of …
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Second primary cancers following breast cancer in the general population and in BRCA1 and BRCA2 pathogenic variant carriers
Background Second primary cancer (SPC) risks in breast cancer (BC) survivors carrying BRCA1 or BRCA2 pathogenic variants (PVs) are uncertain. There is also little evidence for how SPC risks following BC vary by sociodemographic factors, treatments, or the pathology of the first BC. My objectives …
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Long term outcomes of risk reducing salpingo-oophorectomy in the general population and in women with pathogenic variants in BRCA1 and BRCA2
Abstract Background Ovarian cancer is the most lethal gynaecological malignancy. To date there is no approved screening method for ovarian cancer and the only recommended method for prevention is bilateral sapling- oophorectomy (BSO). BSO is associated with more than 90% reduction in the risk of …