Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"contractile ring"”.
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Determining Molecular Mechanisms of Cell Division in Fission Yeast by Testing Major Assumptions of the Search, Capture, Pull, and Release Model of Contractile-Ring Assembly
… Cells from yeast to humans assemble the contractile ring of actin, myosin-II, formin, and other proteins, which constricts to divide the cells. We tested some of the basic assumptions of the search, capture, pull, and release (SCPR) model to explain the mechanism of contractile-ring …
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Investigating the function of Citron kinase and its regulation by other mitotic kinases
… is driven by the constriction of the actomyosin contractile ring that bisects the mother cell and the segregated genomic material. The contractile ring progressively compacts the central spindle microtubules to form an intercellular bridge that contains a small organelle at its centre, known as …
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Mechanisms of Actomyosin Contractility in Cells
… processes hinge on the ability of cells to exert contractile force. Contractility is used by cells to divide, to migrate, to heal wounds, and to pump the heart and move limbs. Contractility is mediated by the actin and myosin cytoskeleton, a dynamic and responsive meshwork that assembles into …
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Characterization of Neuronal Anillin and Borg Protein Localization and Function
… that along with septins, mediates cytokinesis duringcell division. Research to date has focused on characterizing the role of anillin duringcytokinesis. Interestingly, anillin is most highly expressed in the central nervous system,which is in part composed of terminally differentiated, …
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The involvement of ARF6 in rapid membrane recycling during Drosophila spermatocyte cytokinesis
… requires a net increase in the surface area during this constriction. The constriction is driven by formation of an actomyosin contractile ring, and the surface increase by addition of membrane during the formation of the cleavage furrow. Both events depend on the central spindle microtubules …
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An investigation into dystroglycan deficiency in fibroblasts and a role for dystroglycan in cytokinesis
… a possible new function for dystroglycan during cytokinesis. Endogenous dystroglycan was localised to the cleavage furrow and midbody of dividing fibroblasts, where it was found to co-localise with the ERM family member, ezrin. Expression of mutated and truncated dystroglycan-GFP constructs …
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Identification and characterization of genetic interactors of the Rho Guanine-nucleotide exchange factor Pebble in <em>Drosophila</em>
… required for the migration of mesoderm cells during Drosophila gastrulation. The spreading of mesoderm cells is controlled by the FGF signalling pathway acting through the FGF receptor Heartless (Htl). Pbl represents an important downstream component of this FGF pathway and activates the Rho …
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Dynamics of Active Filament Systems
… Strukturen sind Spannungsfasern, kontraktile Ringe oder mitotische Spindeln. Spannungsfasern sind für die Zellbewegung essentiell; sie können kontrahieren und so die Zelle vorwärts bewegen. Die mitotische Spindel trennt Kopien der Erbsubstanz DNS vor der eigentlichen Zellteilung. Der …