Global ETD Search
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Showing 1 to 1 of 1 for “"contact activation system"”.
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A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen
… play a key role in AD onset and progression. The contact activation system, initiated by activation of the plasma protein FXII, is capable of launching both thrombotic and inflammatory pathways. I investigated whether Aβ could directly induce these pathways by interacting with FXII in vitro, in AD …