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Showing 1 to 1 of 1 for “"conliga"”.
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Probabilistic modelling of somatic alterations in bulk tissue and single cells using repeat DNA
… biomedical research. In this thesis, I develop conliga; a probabilistic generative model and associated inference algorithms to infer relative copy number from FAST-SeqS data at the amplicon level. I implement this method in R and C++ and provide the software as an open-source tool. By applying …