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Showing 1 to 12 of 12 for “"conjugative transposons"”.
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Bacteroides Conjugative Transposons: Ecology and Mechanisms
CTnDOT is a 65 kb Bacteroides CTn that carries genes encoding for tetracycline resistance and erythromycin resistance. Previous studies had shown that the attDOT recombination site and integrase of CTnDOT (IntDOT) are sufficient and essential for integration in vivo. Even though the integrase of …
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Activities of Bacteroides Conjugative Transposons: CTnGERM1 and CTnDOT
CTnDOT is a conjugative transposon (CTn) that is found in many Bacteroides strains. Transfer of CTnDOT is stimulated 100--1000 fold if the cells are exposed to tetracycline (Tc). An operon that contains a Tc resistance gene, tetQ, and two regulatory genes, rteA and rteB, is essential for control of …
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Integration and Excision Mechanism of Bacteroides Conjugative Transposons
The third project is about the regulatory mechanism of RteB on CTnDOT. RteA and RteB are shown to be global regulators that regulate many genes on Bacteroides host. Whether RteB regulates CTnDOT and NBU1 excision directly or not is investigated in this study. Both RteB and the mutant are …
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Construction and Use of a System for Studying the Integration of Bacteroides Conjugative Transposons
… is known about the way in which Bacteroides conjugative transposons integrate into their chromosomal target sites, or what the nature of these sites are. In the past, this question has been very difficult to address due to the large size of the Bacteroides conjugative transposons. In this …
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Interactions between the Bacteroides conjugative transposons and the plasmids and insertion elements (NBUs) they mobilize
… and cefoxitin. A family of chromosomally located conjugative transposons is responsible for the spread of tetracycline resistance in the Bacteroides group and is also contributing to the spread of resistance to other antibiotics. Bacteroides conjugative transposons not only transfer themselves but …
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The DNA Transfer Region of Bacteroides Conjugative Transposons Tc(r)Em(r)DOT and Tc(r)ERL
… study of the conjugal transfer genes found on a conjugative transposon. The complete sequence of a functional transfer region is presented and comparative analysis is made between the transfer gene sequences of several conjugative transposons. Two of the newly discovered transfer genes possess …
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The Role of Bacteroides Conjugative Transposons in the Spread of Antibiotic Resistance Genes, And, The Role of recA in DNA Damage Repair in Deincoccus Radiodurans
… segment of DNA, located on a Bacteroides conjugative transposon (CTnBST), that carries a gene for erythromycin resistance (ermB). The same DNA sequence (100% identical) had been previously identified in the genome of Arcanobacterium pyogenes, a gram positive opportunistic pathogen that is …
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Protein/DNA interactions during site-specific recombination
… carry large, integrated elements including conjugative transposons (CTns) and mobilizable transposons (MTns). One such conjugative transposon is CTnDOT, which is 65 kb in size and encodes resistances to tetracycline and erythromycin. In recent years, CTnDOT has been implicated in the spread …
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Mutational Analysis of NBU1 Attachment Sites Reveals a Novel Recombination Mechanism
… has been attributed to mobilizable and related conjugative transposons. NBU1 integrates site specifically into the Bacteroides thetaiotaomicron chromosome primary target site, attBT1-1. NBU1 integrase (IntN1) catalyzes recombination of the NBU1 attachment site, attN1, and the attBT1-1 site. …
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Autonomous replication of integrative and conjugative elements
… other traits, between bacteria. Integrative and conjugative elements (ICEs), also known as conjugative transposons, are a large family of mobile genetic elements that can transfer between neighboring cells. ICEs are found integrated in the chromosome of their host bacterium, where they are …
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Functional Genomic Examinations Of Interactions Between Common Members Of The Human Gut Microbiota
… by lateral gene transfer, including phage and conjugative transposons, as well as by gene duplication. By colonizing germ-free mice with <italic>B. thetaiotaomicron,</italic> or <italic>B. vulgatus,</italic> or both species together, I documented that <italic>B. vulgatus</italic> upregulates …
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Excision of CTnDOT
Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2013-01-24T19:34:21Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Keeton_Carolyn.docx: 6779335 bytes, checksum: 32b917b01d2ce2946ce4c38114fe84a2 (MD5) Keeton_Carolyn.pdf: 4011034 bytes, …