Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 77 for “"congenital heart disease"”.
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Cardiovascular disease in patients with congenital heart disease
Background: Today, about 95% of children with congenital heart disease (CHD) survive into adulthood and the survival in patients with CHD has increased considerably during the last decades. With increasing age, patients with CHD are at an increased risk of developing acquired cardiovascular …
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Engineering Biodegradable Vascular Scaffolds for Congenital Heart Disease
The most common birth defects worldwide are congenital heart defects. To treat these malformations in a child’s cardiovascular system, synthetic grafts have been used as a primary intervention. However, current grafts suffer from deficiencies such as minimal biological compatibility, inability to …
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Adults with congenital heart disease: the patients' perspective.
… resulted in more than 90% of children born with congenital heart disease (CHD) surviving and reaching adulthood. This new patient population has been largely overlooked in recent policy and practice developments in health and social care. Evidence available at the start of the study confirmed …
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3D printing of cardiac structures in congenital heart disease
Congenital heart disease (CHD) is the most common congenital disorder diagnosed in newborns. It afflicts approximately 0.8% to 1.2% of live births worldwide but the mortality rate and incidence vary around the world. CHD is categorized as one or more abnormalities of the heart or great vessels from …
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Modeling Neural Stem Cell Dynamics in Congenital Heart Disease
… these brain regions to severe conditions such as congenital heart disease (CHD), resulting in poor neurological outcomes. Owing to its reminiscent complexity to humans, the neonatal piglet (Sus scrofa domesticus), which possesses a highly evolved gyrencephalic neocortex and an expansive outer SVZ, …
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Physical fitness and exercise in adults with congenital heart disease
Background: The population of patients with adult congenital heart disease (ACHD) is growing, and the estimated life expectancy has increased. Therefore, factors related to lifestyle, such as physical activity (PA), exercise, and the risk of lifestyle-related diseases, to which these patients may …
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Coping Patterns Among Parents of Children with Congenital Heart Disease
Parents of children diagnosed with congenital heart disease (CHD) experience a life filled with unique challenges and stressors. One hundred and eighty-one parents of children with CHD completed online survey that consisted of demographic information, the 3 part Coping Health Inventory for Parents …
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Prenatal Cardiovascular Physiology and Early Neurodevelopment in Cyanotic Congenital Heart Disease
… decrease in mortality of many newborns with congenital heart disease (CHD); however, neurodevelopmental delays and disorders (NDD) are common comorbidities. Studies have demonstrated delays in brain growth and maturation begin as early as the third trimester, with correlations to early …
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Neuropsychological functioning in children with a surgically corrected congenital heart disease
Door een enorme vooruitgang in de pediatrische hartheelkunde over de laatste 35 jaren, worden we geconfronteerd met een steeds groter wordende groep kinderen met een aangeboren hartafwijking (AHA). Ondanks de toegenomen overlevingskansen, blijft morbiditeit echter een grote zorg. Aangeboren …
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Risk Factors Associated With Pressure Injury in Pediatric Congenital Heart Disease Patients
<p>Pediatric congenital heart disease (CHD) patients have unique risk factors associated with the pathophysiology of abnormal heart function. This vulnerable population is likely at an increased risk of acquiring a pressure injury during hospitalization. There are limited studies that include …
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Laboratory Development of a Self-Powered Fontan for Treatment of Congenital Heart Disease
<p>Around 8% of all newborns with a Congenital Heart Defect (CHD) have only a single functioning ventricle. The Fontan operation has served as a palliation for this anomaly for decades, but the surgery entails multiple complications and survival rate is less than 50% by adulthood. A rapidly …
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The extent, impact and stability of cognitive functioning in adult congenital heart disease
… and stability of cognitive functioning in Adult Congenital Heart Disease (ACHD) patients. A cross-sectional and a follow-up study were conducted to address these objectives. The aims of the cross-sectional study were to i) identify the extent of cognitive impairments ii) compare cognitive …
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Magnetic Resonance Imaging - Guided Cardiac Catheterization in Children and Patients with Congenital Heart Disease
L'abstract è presente nell'allegato / the abstract is in the attachment
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AN URBAN BIOETHICS APPROACH TO UNDERSTANDING DISPARITIES IN NEURODEVELOPMENTAL OUTCOMES FOR CHILDREN WITH CONGENITAL HEART DISEASE
Congenital heart disease (CHD) is the most common birth defect and often resultsin neurodevelopmental impairments and psychological problems which impede educational and occupational attainment and decrease overall quality of life into adulthood. While morbidity and mortality outcomes have improved …
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Exploring associations between neuroimaging, neurodevelopment, and emotional reactivity in individuals with or without congenital heart disease
Children with complex congenital heart disease (CHD) experience a range of stressful early life events and are at increased risk of adverse neurodevelopmental and mental health outcomes across life. This thesis, comprising four studies, examines neuroimaging, neurodevelopment, and emotional …
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Trauma, growth and coping in parents of children with congenital heart disease : A mixed methods study.
Background: Raising a child with a congenital heart disease (CHD) can be a difficult experience. Posttraumatic stress symptoms have been observed in parents of children with CHD. However, there is little research investigating post traumatic growth (PTG); or the positive changes following trauma, …
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A Search For Genetic Modifiers Responsible For Congenital Heart Disease Variability In The Presence Of Nkx2-5 Haploinsufficiency
… a clear heritable risk has been observed for congenital heart disease, there is considerable variation in penetrance and presentation likely due to multiple genetic and environmental risk factors. To identify causative factors and interactions responsible for variability in heart development, …
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A review of antenatally-diagnosed congenital heart disease in a Western Cape tertiary facility: outcomes and diagnostic discrepancy
Objective: To describe the cases of fetal congenital heart disease (CHD), the diagnostic discrepancy (DD) between pre- and postnatal echocardiography (echo) and their outcomes in a state tertiary facility in the Western Cape. Study design: A retrospective descriptive study was conducted on 106 …
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In good heart”: a study of the factors associated with health- related quality of life in adult congenital heart disease.
… Health-Related Quality of Life (HRQoL) in Adult Congenital Heart Disease (ACHD). The thesis examines the impact of ACHD on HRQoL, the demographic, clinical, and psychosocial factors associated with HRQoL, and changes in these factors over time. Methods: The thesis consists of three studies, …
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