Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 116 for “"congenital heart"”.
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Engineering Biodegradable Vascular Scaffolds for Congenital Heart Disease
The most common birth defects worldwide are congenital heart defects. To treat these malformations in a child’s cardiovascular system, synthetic grafts have been used as a primary intervention. However, current grafts suffer from deficiencies such as minimal biological compatibility, inability to …
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Adults with congenital heart disease: the patients' perspective.
… resulted in more than 90% of children born with congenital heart disease (CHD) surviving and reaching adulthood. This new patient population has been largely overlooked in recent policy and practice developments in health and social care. Evidence available at the start of the study confirmed …
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3D printing of cardiac structures in congenital heart disease
Congenital heart disease (CHD) is the most common congenital disorder diagnosed in newborns. It afflicts approximately 0.8% to 1.2% of live births worldwide but the mortality rate and incidence vary around the world. CHD is categorized as one or more abnormalities of the heart or great vessels from …
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Modeling Neural Stem Cell Dynamics in Congenital Heart Disease
… these brain regions to severe conditions such as congenital heart disease (CHD), resulting in poor neurological outcomes. Owing to its reminiscent complexity to humans, the neonatal piglet (Sus scrofa domesticus), which possesses a highly evolved gyrencephalic neocortex and an expansive outer SVZ, …
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Congenital Heart Defect-Associated Enhancers Shape Human Cardiomyocyte Lineage Commitment
Pages vii-xiv are misnumbered as pages vi-xiii.
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Coping Patterns Among Parents of Children with Congenital Heart Disease
Parents of children diagnosed with congenital heart disease (CHD) experience a life filled with unique challenges and stressors. One hundred and eighty-one parents of children with CHD completed online survey that consisted of demographic information, the 3 part Coping Health Inventory for Parents …
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Prenatal Cardiovascular Physiology and Early Neurodevelopment in Cyanotic Congenital Heart Disease
… decrease in mortality of many newborns with congenital heart disease (CHD); however, neurodevelopmental delays and disorders (NDD) are common comorbidities. Studies have demonstrated delays in brain growth and maturation begin as early as the third trimester, with correlations to early …
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Neuropsychological functioning in children with a surgically corrected congenital heart disease
Door een enorme vooruitgang in de pediatrische hartheelkunde over de laatste 35 jaren, worden we geconfronteerd met een steeds groter wordende groep kinderen met een aangeboren hartafwijking (AHA). Ondanks de toegenomen overlevingskansen, blijft morbiditeit echter een grote zorg. Aangeboren …
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Integrated approaches to elucidate the genetic architecture of congenital heart defects
Congenital heart defects (CHD) are structural anomalies affecting the heart, are found in 1% of the population and arise during early stages of embryo development. Without surgical and medical interventions, most of the severe CHD cases would not survive after the first year of life. The improved …
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Risk Factors Associated With Pressure Injury in Pediatric Congenital Heart Disease Patients
<p>Pediatric congenital heart disease (CHD) patients have unique risk factors associated with the pathophysiology of abnormal heart function. This vulnerable population is likely at an increased risk of acquiring a pressure injury during hospitalization. There are limited studies that include …
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Pediatric sequential organ failure assessment score in a congenital heart defect population
… patients who suffer from cyanotic and acyanotic congenital heart diseases has not been evaluated. OBJECTIVES: To compare the pSOFA scores between pediatric patients with acyanotic and cyanotic congenital heart disease (CHD). Exampine the pSOFA results of CHD patients with pediatric patients who …
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Laboratory Development of a Self-Powered Fontan for Treatment of Congenital Heart Disease
<p>Around 8% of all newborns with a Congenital Heart Defect (CHD) have only a single functioning ventricle. The Fontan operation has served as a palliation for this anomaly for decades, but the surgery entails multiple complications and survival rate is less than 50% by adulthood. A rapidly …
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Analysing small-sample-sized methylation data to identify biomarkers for congenital heart defects
Congenital Heart Defects (CHDs) are the most common type of human congenital anomaly, representing 0.8~1.2% of infants at birth and accounting for over 40% of prenatal deaths. Although the exact aetiology remains a significant challenge, epigenetic modifications, such as Deoxyribonucleic Acid (DNA) …
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The extent, impact and stability of cognitive functioning in adult congenital heart disease
… and stability of cognitive functioning in Adult Congenital Heart Disease (ACHD) patients. A cross-sectional and a follow-up study were conducted to address these objectives. The aims of the cross-sectional study were to i) identify the extent of cognitive impairments ii) compare cognitive …
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Investigation of Copy Number Variation in South African Patients with Congenital Heart Defects
Background: Congenital heart disease (CHD) is the leading non-infectious cause of paediatric morbidity and mortality worldwide and a significant social and healthcare burden. The aetiology of CHD is poorly understood, though heritable genetic factors including copy number variants (CNVs) have been …
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Personalised warfarin dosing in children after congenital heart surgery using the model-based approach
… dosing using a PK/PD model, in children after congenital heart surgery and to explore the experience of patients/parents and health care professionals with managing long-term warfarin treatment as well as their experience with the model-based dosing approach. The predictive performance of the …
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An evaluation of genomic factors and their importance in etiopathogenesis of congenital heart diseases /
Congenital heart diseases (CHDs) are the most frequent congenital developmental anomalies in infancy, diagnosed to 8 out of 1000 liveborn infants. Some of CHDs have a poor prediction of survival and are among the major causes of non-infectious death in neonatancy. The etiology of a majority of CHDs …
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Single-Center Experience of Providing Congenital Heart Surgery to Low- and Middle-Income Countries
… of this study is to analyze the demographics of congenital heart disease (CHD) patients from over 50 low- and middle-income countries (LMICs) who received care at Frontier Lifeline Hospital (FLL), a specialty cardiac center in Chennai, India, and identify the barriers and limitations they faced. …
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Magnetic Resonance Imaging - Guided Cardiac Catheterization in Children and Patients with Congenital Heart Disease
L'abstract è presente nell'allegato / the abstract is in the attachment
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