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Showing 1 to 8 of 8 for “"conformational relaxation"”.
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Structural heterogeneity and conformational relaxation in heme proteins
… heterogeneity of protein solutions, and that conformational substates are an intrinsic part of protein systems.
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Conformational Relaxation and Kinetic Hole-Burning in Sperm Whale Myoglobin
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1988.
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Conformational relaxation and kinetic hole-burning in sperm whale myoglobin
… different mechanisms: kinetic hole-burning and conformational relaxation. Kinetic hole-burning results from different parts of an inhomogeneously broadened spectrum rebinding with different rates. Conformational relaxation is a change in the protein structure toward the deoxy structure. An …
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Conformational relaxation in heme proteins: Ligand rebinding above the glass transition
… barriers, $g(H)$. This work addresses the relaxation of the enthalpic barriers that sets in near the glass transition of the solvent as significant protein motions occur on the time scale of rebinding. As the heme domes fully toward its equilibrium deoxy structure, the distribution of …
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Conformational relaxation in heme proteins : ligand rebinding above the glass transition
… barriers, g(H). This work addresses the relaxation of the enthalpic barriers that sets in near the glass transition of the solvent as significant protein motions occur on the time scale of rebinding. As the heme domes fully toward its equilibrium deoxy structure, the distribution of …
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The kinetics of protein conformational relaxation in sperm whale myoglobin following a pressure jump
… data are consistent with hierarchically ordered conformational substates, csn' (nth tier), for the protein-ligand-solvent system. The spectra can be resolved into three bands: Ao at -1966 cm-1, A1 at -1946 cm-1 and A3 at -1933 cm-1. The areas of the A bands are correlated with cso. Fits to the …
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The role of conformational motions in the control of ligand binding to myoglobin and hemoglobin
… and time (30ns to lOOs). Our data show that the conformational relaxation of the Fe out-of-plane distance proceeds in discrete steps which can be correlated with peaks in the rebinding lifetime distribution, j(logt). In addition we show that this conformational relaxation can be enhanced through …
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The effects of extended illumination on CO rebinding to myoglobin
… effects of illumination are compared with the conformational relaxation of MbCO that slows down rebinding at temperatures above 160K. There are some features in common with this relaxation, but also significant differences. Finally, a mechanism for the temperature dependence of the effects is …