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Showing 1 to 5 of 5 for “"condensins"”.

  1. Linker Histone Medicated Regulation of Mitotic Chromosome Compaction and Individualization

    … segregation. Recent studies have shown how condensins and DNA topoisomerase II organize the mitotic chromosome. However, the regulation of these factors in maintaining proper chromosome size in different cell types remains a mystery. Here, I investigated the role of the linker histone …

    rockefeller Repository record for Linker Histone Medicated Regulation of Mitotic Chromosome Compaction and Individualization (opens in a new tab)

  2. Mechanisms for maintaining genomic integrity during chromosome segregation in budding yeast

    … Here we show that Lrs4 and Csml collaborate with condensins at kinetochores to control mitotic and meiotic chromosome segregation. During meiosis, diploid cells must first segregate homologous chromosomes before sister chromatids can separate. Lrs4-Csml and condensin are required during the first …

    mit Repository record for Mechanisms for maintaining genomic integrity during chromosome segregation in budding yeast (opens in a new tab)

  3. Large-Scale Structure of Mitotic Chromosomes

    … We showed, however, that the amounts of condensins and phosphorylated histone H3 inside vector concatamers were similar to surrounding chromosomal arms in both expressing and not expressing GFP-lacI cells."

    uiuc Repository record for Large-Scale Structure of Mitotic Chromosomes (opens in a new tab)

  4. Patterns and processes driving chromosome organization

    … interactions between loop extruding Cohesins and Condensins. We find that non-trivial interactions between these complexes are required to accurately capture the dynamics of the data. Our findings extend the model of loop extrusion and highlight the role of interactions between SMC complexes in …

    mit Repository record for Patterns and processes driving chromosome organization (opens in a new tab)

  5. Genome organization by loop extrusion

    … loops form by the differential action of the two condensins while condensin II is required for helical winding.

    mit Repository record for Genome organization by loop extrusion (opens in a new tab)